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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1977-4-30
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pubmed:abstractText |
Intravenous infusions of [Sar1-Ala8]angiotensin II, acute hypophysectomy, and acute intestinal denervation were carried out in 15 pentobarbital-anesthetized cats. Infusion of the angiotensin II antagonist caused only a small increase in superior mesenteric arterial conductance and a small decrease in arterial pressure in intact animals, but the changes were subypophysectomy alone caused only a small intestinal vasodilatation and little change in arterial pressure. However, the responses to hypophysectomy were much larger when the gland was removed during a prolonged infusion of the angiotensin II antagonist. Intestinal denervation caused only minor changes in mesenteric conductance and arterial pressure, and the responses to [Sar1-Ala8]angiotensin II and hypophysectomy were largely unaltered by the presence or absence of the intestinal innervation. The results suggest that the renin-angiotensin and vasopressin systems are reciprocal overlapping mechanisms that exert a significant vasoconstrictor influence on the intestinal resistance vessels in the anesthetized cat. In the absence of one control system, the other appears to compensate to maintain resistance.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0002-9513
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
232
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
H260-6
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:842681-Angiotensin II,
pubmed-meshheading:842681-Animals,
pubmed-meshheading:842681-Blood Pressure,
pubmed-meshheading:842681-Cats,
pubmed-meshheading:842681-Denervation,
pubmed-meshheading:842681-Hypophysectomy,
pubmed-meshheading:842681-Intestines,
pubmed-meshheading:842681-Mesentery,
pubmed-meshheading:842681-Renin,
pubmed-meshheading:842681-Saralasin,
pubmed-meshheading:842681-Vascular Resistance,
pubmed-meshheading:842681-Vasopressins
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pubmed:year |
1977
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pubmed:articleTitle |
Vasopressin and angiotensin: reciprocal mechanisms controlling mesenteric conductance.
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pubmed:publicationType |
Journal Article
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