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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1993-2-23
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pubmed:abstractText |
EEGs, brainstem auditory evoked potentials (BAEPs) and auditory event-related potentials (ERPs) were recorded from 33 individuals infected with the human immunodeficiency virus, type 1 (HIV1+ patients: 13 CDC Class II or III; 20 Class IV). All were neurologically asymptomatic, non-demented, and had a past history of intravenous drug abuse. Sixteen age- and sex-matched normals and 10 HIV1- former drug addicts served as controls. Half of the HIV1+ and HIV1- subjects displayed mild EEG anomalies and, except for one HIV1+ patient, BAEPs were normal in both groups. ERPs were normal in all HIV1- subjects but anomalous (longer latencies of components P2, N2, P3; reduced amplitude of P3) in 9 HIV1+ patients (27%), the incidence of such anomalies being higher for Class IV than Class II/III patients. Auditory ERPs proved the most sensitive and specific of these electrophysiological procedures in detecting subclinical central nervous system involvement in HIV1 infection.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0001-6314
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
87
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
47-51
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8424311-Adult,
pubmed-meshheading:8424311-Analysis of Variance,
pubmed-meshheading:8424311-Brain,
pubmed-meshheading:8424311-Electroencephalography,
pubmed-meshheading:8424311-Evoked Potentials,
pubmed-meshheading:8424311-Evoked Potentials, Auditory, Brain Stem,
pubmed-meshheading:8424311-Female,
pubmed-meshheading:8424311-HIV Seropositivity,
pubmed-meshheading:8424311-HIV-1,
pubmed-meshheading:8424311-Humans,
pubmed-meshheading:8424311-Male,
pubmed-meshheading:8424311-Neuropsychological Tests
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pubmed:year |
1993
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pubmed:articleTitle |
Electrophysiological study of neurologically asymptomatic HIV1 seropositive patients.
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pubmed:affiliation |
Department of Neurological and Psychiatric Science, University of Florence, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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