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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1993-2-19
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pubmed:abstractText |
We present here the genetic mapping of the alpha-skeletal actin locus (Actsk-1) on mouse Chromosome (Chr) 8, on the basis of the PCR analysis of a microsatellite in an interspecific backcross. Linkage and genetic distances were established for four loci by analysis of 192 (or 222) meiotic events and indicated the following gene order: (centromere)-Es-1-11.7 cM-Tat-8.3 cM-Actsk-1-0.5 cM-Aprt. Mapping of ACTSK to human Chr 1 and of TAT and APRT to human Chr 16 demonstrates the existence of a new short region of homology between mouse Chr 8 and human Chr 1. Intermingling on this scale between human and mouse chromosomal homologies that occurred during evolution creates disorders in comparative linkage studies.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0938-8990
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
4
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pubmed:geneSymbol |
Actsk-1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
15-20
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8422497-Actins,
pubmed-meshheading:8422497-Adenine Phosphoribosyltransferase,
pubmed-meshheading:8422497-Animals,
pubmed-meshheading:8422497-Base Sequence,
pubmed-meshheading:8422497-Chromosome Mapping,
pubmed-meshheading:8422497-Chromosomes, Human, Pair 1,
pubmed-meshheading:8422497-Chromosomes, Human, Pair 16,
pubmed-meshheading:8422497-DNA, Satellite,
pubmed-meshheading:8422497-Humans,
pubmed-meshheading:8422497-Hybrid Cells,
pubmed-meshheading:8422497-Mice,
pubmed-meshheading:8422497-Mice, Inbred Strains,
pubmed-meshheading:8422497-Molecular Sequence Data,
pubmed-meshheading:8422497-Polymerase Chain Reaction
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pubmed:year |
1993
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pubmed:articleTitle |
Re-localization of Actsk-1 to mouse chromosome 8, a new region of homology with human chromosome 1.
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pubmed:affiliation |
Unité de Génétique Moléculaire du Développement, URA 1148, Institut Pasteur, Paris, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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