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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1993-2-17
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pubmed:databankReference |
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pubmed:abstractText |
A cDNA encoding rat intestinal 15 kDa protein was isolated and sequenced from a rat ileum-specific cDNA library. This cDNA was found to contain an open reading frame of 384 nucleotides as well as 5' (27 nucleotides) and 3' (46 nucleotides) non-coding regions. The deduced sequence of 127 amino acids was identical to that of rat I-15P which was purified from rat intestinal epithelium. The nucleotide sequence of the open reading frame exhibited 79% identity to that of the porcine gastrotropin. Northern blot analysis indicated that the same size of transcript as that of the ileum was detected in the ovary, suggesting that I-15P or a homologous protein might be involved in the metabolism of steroids in steroid hormone-producing tissues.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0006-291X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
190
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
175-80
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pubmed:dateRevised |
2008-7-17
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pubmed:meshHeading |
pubmed-meshheading:8422242-Amino Acid Sequence,
pubmed-meshheading:8422242-Animals,
pubmed-meshheading:8422242-Base Sequence,
pubmed-meshheading:8422242-Carrier Proteins,
pubmed-meshheading:8422242-Cloning, Molecular,
pubmed-meshheading:8422242-DNA,
pubmed-meshheading:8422242-Fatty Acid-Binding Proteins,
pubmed-meshheading:8422242-Female,
pubmed-meshheading:8422242-Gastrointestinal Hormones,
pubmed-meshheading:8422242-Gene Library,
pubmed-meshheading:8422242-Ileum,
pubmed-meshheading:8422242-Male,
pubmed-meshheading:8422242-Molecular Sequence Data,
pubmed-meshheading:8422242-Molecular Weight,
pubmed-meshheading:8422242-Muscle, Smooth,
pubmed-meshheading:8422242-Neoplasm Proteins,
pubmed-meshheading:8422242-Nerve Tissue Proteins,
pubmed-meshheading:8422242-Open Reading Frames,
pubmed-meshheading:8422242-Organ Specificity,
pubmed-meshheading:8422242-Ovary,
pubmed-meshheading:8422242-Polymerase Chain Reaction,
pubmed-meshheading:8422242-Rats,
pubmed-meshheading:8422242-Rats, Sprague-Dawley,
pubmed-meshheading:8422242-Sequence Homology, Nucleic Acid,
pubmed-meshheading:8422242-Swine,
pubmed-meshheading:8422242-Transcription, Genetic
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pubmed:year |
1993
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pubmed:articleTitle |
Cloning of a cDNA encoding rat intestinal 15 kDa protein and its tissue distribution.
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pubmed:affiliation |
Department of Biochemistry, Niigata University School of Medicine, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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