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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1993-2-11
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pubmed:abstractText |
Bullous pemphigoid is usually treated with systemic corticosteroids. Side effects are common in elderly patients, justifying the search for adjuvant therapy. This randomized, multicentric unblind study was designed to assess the efficacy of azathioprine or plasma exchange when added to conventional doses of prednisolone. One hundred patients with active disease entered the study. They were randomly allocated to receive 28 days of treatment with oral prednisolone sodium metasulfobenzoate (1 mg/kg per day) either alone or in combination with oral azathioprine (100 to 150 mg/d) or four large-volume plasma exchanges. After 28 days, the prednisolone doses were progressively decreased according to the same strict regimen in the three groups (in combination with oral azathioprine in group 2).
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0003-987X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
129
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pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
49-53
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pubmed:dateRevised |
2010-3-24
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pubmed:meshHeading |
pubmed-meshheading:8420491-Aged,
pubmed-meshheading:8420491-Azathioprine,
pubmed-meshheading:8420491-Combined Modality Therapy,
pubmed-meshheading:8420491-Drug Therapy, Combination,
pubmed-meshheading:8420491-Female,
pubmed-meshheading:8420491-Humans,
pubmed-meshheading:8420491-Male,
pubmed-meshheading:8420491-Pemphigoid, Bullous,
pubmed-meshheading:8420491-Plasma Exchange,
pubmed-meshheading:8420491-Prednisolone
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pubmed:year |
1993
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pubmed:articleTitle |
Controlled trial of azathioprine and plasma exchange in addition to prednisolone in the treatment of bullous pemphigoid.
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pubmed:affiliation |
Department of Dermatology, Hôpital H. Mondor, Créteil, France.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
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