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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1993-2-5
|
| pubmed:abstractText |
One hundred seventy-two patients with 1-vessel disease documented at predischarge angiography who had been followed for 43 +/- 30 months after an initial Q-wave acute myocardial infarction were retrospectively evaluated to investigate the prognostic value of infarct-related artery patency and left ventricular (LV) function. Multiple logistic regression analysis revealed that only infarct artery patency (Thrombolysis in Myocardial Infarction [TIMI] grades 2-3 vs 0-1) (Z = 2.24; p < 0.05) and end-systolic volume index (Z = -2.67; p < 0.01) were independently related to survival. Sixteen cardiac deaths were observed; all 16 patients had LV dysfunction (defined as end-systolic volume index > 40 ml/m2), and 15 had an occluded infarct-related artery. In the subgroup with LV dysfunction, the 10-year percent survival rate was 20% among patients with TIMI grade 0 to 1 versus 96% with grade 2-3 (p < 0.001). Patency of the infarct-related artery was also the only independent predictor of recurrent ischemia (Z = 2.59; p < 0.01). In conclusion, both infarct-related artery patency and LV function are independent predictors of survival after Q-wave acute myocardial infarction. Patients with normal LV function have an excellent long-term prognosis, which is only partially counterbalanced by the tendency toward clinical instability observed in those with an open infarct-related vessel. However, when an occluded infarct-related artery is observed in the setting of LV dysfunction, the long-term outcome appears to be relatively poor.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jan
|
| pubmed:issn |
0002-9149
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
1
|
| pubmed:volume |
71
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| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1-7
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:8420223-Cardiac Volume,
pubmed-meshheading:8420223-Collateral Circulation,
pubmed-meshheading:8420223-Coronary Angiography,
pubmed-meshheading:8420223-Coronary Circulation,
pubmed-meshheading:8420223-Coronary Vessels,
pubmed-meshheading:8420223-Electrocardiography,
pubmed-meshheading:8420223-Follow-Up Studies,
pubmed-meshheading:8420223-Humans,
pubmed-meshheading:8420223-Incidence,
pubmed-meshheading:8420223-Middle Aged,
pubmed-meshheading:8420223-Myocardial Infarction,
pubmed-meshheading:8420223-Prognosis,
pubmed-meshheading:8420223-Recurrence,
pubmed-meshheading:8420223-Retrospective Studies,
pubmed-meshheading:8420223-Stroke Volume,
pubmed-meshheading:8420223-Survival Rate,
pubmed-meshheading:8420223-Thrombolytic Therapy,
pubmed-meshheading:8420223-Vascular Patency,
pubmed-meshheading:8420223-Ventricular Function, Left
|
| pubmed:year |
1993
|
| pubmed:articleTitle |
Patency of the infarct-related artery and left ventricular function as the major determinants of survival after Q-wave acute myocardial infarction.
|
| pubmed:affiliation |
Divisione di Cardiologia, Ospedale G.B. Morgagni-L. Pierantoni, Forlí, Italy.
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| pubmed:publicationType |
Journal Article
|