Linked Life Data

8419636

Source:http://linkedlifedata.com/resource/pubmed/id/8419636

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1993-2-11
pubmed:databankReference
pubmed:abstractText
The high prevalences of antibodies against human T-cell leukemia (lymphotropic) virus type I (HTLV-I) reported for remote populations in Papua New Guinea and the Solomon Islands and for some aboriginal populations in Australia have been verified by virus isolation. Limited genetic analysis of the transmembrane portion (gp21) of the envelope gene of these viruses indicates the existence of highly divergent HTLV-I strains in Melanesia. Here, we report the complete nucleotide sequence of an HTLV-I isolate (designated HTLV-IMEL5) from the Solomon Islands. The overall nucleotide divergence of HTLV-IMEL5 from the prototype HTLV-IATK was approximately 8.5%. The degree of variability in the amino acid sequences of structural genes ranged between 3 and 11% and was higher (8.5 to 25%) for the regulatory (tax and rex) genes and the other genes encoded by the pX region. Since HTLV-IMEL5 was as distantly related to HTLV-II as to the other known HTLV-I strains, it could not have arisen from a reocmbinational event involving HTLV-II but rather might be an example of independent viral evolution in this remote population. These data provide important insights and raise new questions about the origin and global dissemination of HTLV-I.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-1310774, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-1326649, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-1348363, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-1528897, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-1548762, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-1548780, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-1711082, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-1712105, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-1716024, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-1760230, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-1869834, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-1881912, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-1911545, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-1996344, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-2002547, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-2024459, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-2024477, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-2041093, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-2116986, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-2146511, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-2241626, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-2304144, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-2353464, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-2422659, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-2428880, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-2476442, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-2528586, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-2562124, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-2563272, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-2582407, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-2602375, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-2677406, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-2863442, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-2897612, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-2990028, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-2992082, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-2999613, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-3001699, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-3021974, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-3025015, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-3035544, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-3048703, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-6261256, http://linkedlifedata.com/resource/pubmed/commentcorrection/8419636-6304725
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0022-538X
pubmed:author
pubmed:issnType
Print
pubmed:volume
67
pubmed:geneSymbol
env, gag, pol
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1015-23
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
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