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rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
1993-2-4
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|
pubmed:abstractText |
Alveolar and embryonal rhabdomyosarcomas are soft-tissue tumors that occur mainly in childhood. The more aggressive alveolar subtype has been found to possess a characteristic chromosomal abnormality located near the retinoblastoma susceptibility gene (RB1). RB1 is a tumor suppressor gene implicated in the development of retinoblastoma and other, unrelated malignancies, especially osteogenic sarcomas and other second malignancies in retinoblastoma survivors.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jan
|
|
pubmed:issn |
0027-8874
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|
pubmed:author |
|
|
pubmed:issnType |
Print
|
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pubmed:day |
20
|
|
pubmed:volume |
85
|
|
pubmed:geneSymbol |
RB1
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
152-7
|
|
pubmed:dateRevised |
2006-11-15
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|
pubmed:meshHeading |
pubmed-meshheading:8418305-Breast Neoplasms,
pubmed-meshheading:8418305-Child,
pubmed-meshheading:8418305-Eye Neoplasms,
pubmed-meshheading:8418305-Female,
pubmed-meshheading:8418305-Fluorescent Antibody Technique,
pubmed-meshheading:8418305-Genes, Retinoblastoma,
pubmed-meshheading:8418305-Genetic Predisposition to Disease,
pubmed-meshheading:8418305-Humans,
pubmed-meshheading:8418305-Immunohistochemistry,
pubmed-meshheading:8418305-RNA, Messenger,
pubmed-meshheading:8418305-RNA, Neoplasm,
pubmed-meshheading:8418305-Retinoblastoma,
pubmed-meshheading:8418305-Retinoblastoma Protein,
pubmed-meshheading:8418305-Rhabdomyosarcoma,
pubmed-meshheading:8418305-Tumor Cells, Cultured
|
|
pubmed:year |
1993
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|
pubmed:articleTitle |
Expression of the retinoblastoma susceptibility gene in childhood rhabdomyosarcomas.
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|
pubmed:affiliation |
Department of Pathology and Laboratory Medicine, Childrens Hospital Los Angeles, CA 90027.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
