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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1993-2-4
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pubmed:abstractText |
The serum level of IL-6 and expression of IL-6 mRNA in hepatocytes from regenerating liver were investigated in the rat. The IL-6 level in the serum was not significantly different from that of a control group of rats submitted to an acute experimental inflammation. IL-6 mRNA expression did not occur in the liver of hepatectomized rats as judged from Northern blotting experiments using an IL-6 riboprobe. These results suggest that if IL-6 is implicated in hepatic regeneration, this cytokine is not produced by the regenerating liver and must be delivered exogenously to the liver to modulate hepatic regeneration.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
0014-5793
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
4
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pubmed:volume |
315
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
159-62
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:8417972-Animals,
pubmed-meshheading:8417972-Gene Expression,
pubmed-meshheading:8417972-Interleukin-6,
pubmed-meshheading:8417972-Liver,
pubmed-meshheading:8417972-Liver Regeneration,
pubmed-meshheading:8417972-Male,
pubmed-meshheading:8417972-RNA, Messenger,
pubmed-meshheading:8417972-Rats,
pubmed-meshheading:8417972-Rats, Sprague-Dawley,
pubmed-meshheading:8417972-Turpentine
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pubmed:year |
1993
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pubmed:articleTitle |
Absence of expression of interleukin-6 (IL-6) mRNA in regenerating rat liver.
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pubmed:affiliation |
INSERM Unité 78, Bois-Guillaume, France.
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pubmed:publicationType |
Journal Article
|