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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1993-1-21
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pubmed:abstractText |
Patients seen at a pediatric lipid clinic over a 27-month period were reviewed retrospectively to evaluate types of primary lipid disorders and effect of dietary treatment at the first follow-up visit. One hundred eighty-two patients were classified into one of four categories: (1) elevated low-density lipoprotein cholesterol (LDL-C) with LDL-C > 95th percentile (32%); (2) isolated triglyceride (TG)/high-density lipoprotein cholesterol (HDL-C) abnormalities, with TG > 95th percentile and/or HDL-C < 5th percentile (30%); (3) borderline LDL-C, TG, or HDL-C (29%); (4) normal (9%). The American Heart Association Step-One Diet was prescribed for all patients older than 2 years, and they received extensive nutritional and risk-management counseling. Of these patients, 59 (32%) returned for at least one follow-up visit and mean changes in lipid values between initial and first follow-up visits were evaluated. Levels of LDL-C decreased by 24 mg/dL in 22 patients with elevated LDL-C levels. Triglyceride levels decreased by a mean of 22 mg/dL and HDL-C increased by a mean of 4 mg/dL in 21 patients with isolated TG/HDL-C abnormalities. Levels of LDL-C tended to rise in this group, but not to a significant degree. A new finding of this report is that screening for total cholesterol results in the identification of many children with TG or HDL-C abnormalities alone and that the Step-One Diet appears to be effective in improving both TG and HDL-C levels in these patients.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0031-4005
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
91
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
92-6
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:8416512-Adolescent,
pubmed-meshheading:8416512-Adult,
pubmed-meshheading:8416512-Child,
pubmed-meshheading:8416512-Child, Preschool,
pubmed-meshheading:8416512-Cholesterol, HDL,
pubmed-meshheading:8416512-Cholesterol, LDL,
pubmed-meshheading:8416512-Counseling,
pubmed-meshheading:8416512-Dietary Fats,
pubmed-meshheading:8416512-Female,
pubmed-meshheading:8416512-Follow-Up Studies,
pubmed-meshheading:8416512-Health Education,
pubmed-meshheading:8416512-Hospitals, Pediatric,
pubmed-meshheading:8416512-Humans,
pubmed-meshheading:8416512-Hyperlipidemias,
pubmed-meshheading:8416512-Infant,
pubmed-meshheading:8416512-Male,
pubmed-meshheading:8416512-Mass Screening,
pubmed-meshheading:8416512-Nutritional Sciences,
pubmed-meshheading:8416512-Ohio,
pubmed-meshheading:8416512-Outpatient Clinics, Hospital,
pubmed-meshheading:8416512-Retrospective Studies,
pubmed-meshheading:8416512-Seroepidemiologic Studies,
pubmed-meshheading:8416512-Triglycerides
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pubmed:year |
1993
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pubmed:articleTitle |
Primary hyperlipidemia in a pediatric population: classification and effect of dietary treatment.
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pubmed:affiliation |
Dept of Pediatrics, Children's Hospital Medical Center, Cincinnati, OH 45229-2899.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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