Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1993-1-21
pubmed:abstractText
Patients seen at a pediatric lipid clinic over a 27-month period were reviewed retrospectively to evaluate types of primary lipid disorders and effect of dietary treatment at the first follow-up visit. One hundred eighty-two patients were classified into one of four categories: (1) elevated low-density lipoprotein cholesterol (LDL-C) with LDL-C > 95th percentile (32%); (2) isolated triglyceride (TG)/high-density lipoprotein cholesterol (HDL-C) abnormalities, with TG > 95th percentile and/or HDL-C < 5th percentile (30%); (3) borderline LDL-C, TG, or HDL-C (29%); (4) normal (9%). The American Heart Association Step-One Diet was prescribed for all patients older than 2 years, and they received extensive nutritional and risk-management counseling. Of these patients, 59 (32%) returned for at least one follow-up visit and mean changes in lipid values between initial and first follow-up visits were evaluated. Levels of LDL-C decreased by 24 mg/dL in 22 patients with elevated LDL-C levels. Triglyceride levels decreased by a mean of 22 mg/dL and HDL-C increased by a mean of 4 mg/dL in 21 patients with isolated TG/HDL-C abnormalities. Levels of LDL-C tended to rise in this group, but not to a significant degree. A new finding of this report is that screening for total cholesterol results in the identification of many children with TG or HDL-C abnormalities alone and that the Step-One Diet appears to be effective in improving both TG and HDL-C levels in these patients.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0031-4005
pubmed:author
pubmed:issnType
Print
pubmed:volume
91
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
92-6
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed-meshheading:8416512-Adolescent, pubmed-meshheading:8416512-Adult, pubmed-meshheading:8416512-Child, pubmed-meshheading:8416512-Child, Preschool, pubmed-meshheading:8416512-Cholesterol, HDL, pubmed-meshheading:8416512-Cholesterol, LDL, pubmed-meshheading:8416512-Counseling, pubmed-meshheading:8416512-Dietary Fats, pubmed-meshheading:8416512-Female, pubmed-meshheading:8416512-Follow-Up Studies, pubmed-meshheading:8416512-Health Education, pubmed-meshheading:8416512-Hospitals, Pediatric, pubmed-meshheading:8416512-Humans, pubmed-meshheading:8416512-Hyperlipidemias, pubmed-meshheading:8416512-Infant, pubmed-meshheading:8416512-Male, pubmed-meshheading:8416512-Mass Screening, pubmed-meshheading:8416512-Nutritional Sciences, pubmed-meshheading:8416512-Ohio, pubmed-meshheading:8416512-Outpatient Clinics, Hospital, pubmed-meshheading:8416512-Retrospective Studies, pubmed-meshheading:8416512-Seroepidemiologic Studies, pubmed-meshheading:8416512-Triglycerides
pubmed:year
1993
pubmed:articleTitle
Primary hyperlipidemia in a pediatric population: classification and effect of dietary treatment.
pubmed:affiliation
Dept of Pediatrics, Children's Hospital Medical Center, Cincinnati, OH 45229-2899.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't