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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1977-4-30
|
| pubmed:abstractText |
Isolation of two C(17)-C(20) rotamers of 20-methyl-20-(2-hydroxyethoxy)-5-pregnene-3beta, 17alpha-diol has been reported. X-Ray analysis of a diacetate derivative of one of the "rotamers" shows that the actual structure is 3beta-acetoxy-17aalpha-(2-acetoxyethoxy)-17alpha,17abeta-dimethyl-D-homo-5-androsten-17beta-ol (C28H44O6). Thus, although this investigation refutes the existence of C(17)-C(20) rotamers, it suggests a possible new pathway for D-homo steroid synthesis.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
0039-128X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
29
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
261-70
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:841624-Homosteroids,
pubmed-meshheading:841624-Isomerism,
pubmed-meshheading:841624-Magnetic Resonance Spectroscopy,
pubmed-meshheading:841624-Models, Molecular,
pubmed-meshheading:841624-Molecular Conformation,
pubmed-meshheading:841624-Pregnenes,
pubmed-meshheading:841624-Spectrophotometry, Infrared,
pubmed-meshheading:841624-Structure-Activity Relationship,
pubmed-meshheading:841624-X-Ray Diffraction
|
| pubmed:year |
1977
|
| pubmed:articleTitle |
A steroid structure which refutes the isolation of C(17)-C(20) rotational isomers.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|