Linked Life Data

8415448

Source:http://linkedlifedata.com/resource/pubmed/id/8415448

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
22
pubmed:dateCreated
1993-10-27
pubmed:abstractText
From studies on embryogenesis, the authors describe the development, not conditioned by sex steroids, of the upper female genital tract and, in particular, the formation of its cervico-vaginal portion and the shaping of the uterine cervix in about the 16th week of pregnancy. Basing themselves on the physiology of the foeto-placental unit and on the hormonal profile of the foetal ovary, they show that the action of oestrogens on the foetal uterine cervix can be observed only from the 32nd week onward. The action of diethylstilboestrol--a potent oestrogen that is not steroidal and therefore not degraded by foetal metabolism--on the foetal genital tract is explained. An excessive development of the uterine canal caudal part determines structural anomalies of the uterine cervix at birth, the T shape of the uterine cavity and the vaginal diaphragms. The aetiogenesis of clear-cell adenocarcinoma in the cervico-vaginal portion is discussed.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0755-4982
pubmed:author
pubmed:issnType
Print
pubmed:day
19
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1052-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
[From embryogenesis to pathogenesis of effects of diethylstilbestrol on the female genital tract].
pubmed:affiliation
Service central d'Anatomie et de Cytologie pathologiques, CHU d'Amiens.
pubmed:publicationType
Journal Article, English Abstract