Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1993-11-10
|
pubmed:abstractText |
We have previously shown that the concentration of Gd-DTPA as a function of time ([Gd-DTPA]t(t)) in the myocardium following an intravenous bolus injection of Gd-DTPA can be modeled using the Modified Kety Equation. Fitting this model to measurements of [Gd-DTPA]t(t) in a region of myocardium would allow the determination of myocardial distribution volume (lambda) and the product of flow (F) and extraction efficiency (E), i.e., FE. Thus, to measure F, E must be known. We describe here techniques developed to measure local values of E in normal and diseased myocardium. These techniques are valid for any inert diffusible MR contrast agent.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Contrast Media,
http://linkedlifedata.com/resource/pubmed/chemical/Gadolinium,
http://linkedlifedata.com/resource/pubmed/chemical/Gadolinium DTPA,
http://linkedlifedata.com/resource/pubmed/chemical/Organometallic Compounds,
http://linkedlifedata.com/resource/pubmed/chemical/Pentetic Acid
|
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0740-3194
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
30
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
332-6
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:8412604-Animals,
pubmed-meshheading:8412604-Contrast Media,
pubmed-meshheading:8412604-Coronary Circulation,
pubmed-meshheading:8412604-Dogs,
pubmed-meshheading:8412604-Gadolinium,
pubmed-meshheading:8412604-Gadolinium DTPA,
pubmed-meshheading:8412604-Magnetic Resonance Imaging,
pubmed-meshheading:8412604-Myocardial Ischemia,
pubmed-meshheading:8412604-Myocardium,
pubmed-meshheading:8412604-Organometallic Compounds,
pubmed-meshheading:8412604-Pentetic Acid
|
pubmed:year |
1993
|
pubmed:articleTitle |
Techniques for the measurement of the local myocardial extraction efficiency for inert diffusible contrast agents such as gadopentate dimeglumine.
|
pubmed:affiliation |
Department of Physics, Lawson Research Institute, St. Joseph's Health Centre, University of Western Ontario, London, Canada.
|
pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
|