| pubmed-article:8410062 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8410062 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
| pubmed-article:8410062 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:8410062 | lifeskim:mentions | umls-concept:C0007776 | lld:lifeskim |
| pubmed-article:8410062 | lifeskim:mentions | umls-concept:C0022655 | lld:lifeskim |
| pubmed-article:8410062 | lifeskim:mentions | umls-concept:C0001613 | lld:lifeskim |
| pubmed-article:8410062 | lifeskim:mentions | umls-concept:C0020672 | lld:lifeskim |
| pubmed-article:8410062 | lifeskim:mentions | umls-concept:C0740391 | lld:lifeskim |
| pubmed-article:8410062 | lifeskim:mentions | umls-concept:C0851827 | lld:lifeskim |
| pubmed-article:8410062 | lifeskim:mentions | umls-concept:C1701901 | lld:lifeskim |
| pubmed-article:8410062 | lifeskim:mentions | umls-concept:C0205374 | lld:lifeskim |
| pubmed-article:8410062 | lifeskim:mentions | umls-concept:C1883709 | lld:lifeskim |
| pubmed-article:8410062 | lifeskim:mentions | umls-concept:C2926735 | lld:lifeskim |
| pubmed-article:8410062 | pubmed:issue | 1-2 | lld:pubmed |
| pubmed-article:8410062 | pubmed:dateCreated | 1993-11-1 | lld:pubmed |
| pubmed-article:8410062 | pubmed:abstractText | We investigated the effect of post-ischemic 30 degrees C hypothermia on transient middle cerebral artery (MCA) occlusion in the rat. Male Wistar rats (n = 27) were subjected MCA occlusion for 2 h by inserting a nylon filament into the internal carotid artery. Three groups of animals were studied: 1) normothermic ischemia and normothermic reperfusion (n = 13), 2) normothermic ischemia and 1 h of hypothermic reperfusion (n = 6), 3) normothermic ischemia and 3 h of hypothermic reperfusion (n = 6); monitoring of cerebral temperatures were performed on two additional rats. The animals were sacrificed after one week, and coronal sections were obtained and stained with hematoxylin and eosin (H/E) for histopathological examination and determination of infarct volume. The data indicate that both normothermic reperfusion and 1 h hypothermic reperfusion groups exhibited similar infarct volumes in the cortex and the basal ganglia, respectively (P > 0.1). The 3 h post-ischemic hypothermia group revealed a significant decrease in infarct volume in the cortex compared to the normothermic group (P < 0.05). However, the infarct volume of the basal ganglia was not significantly lessened by the 3 h post-ischemic hypothermia. Thus 3 h post-ischemic hypothermia provides preferential reduction of cell damage in the cortex, from 2 h of MCA occlusion in the rat. | lld:pubmed |
| pubmed-article:8410062 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8410062 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8410062 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8410062 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8410062 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8410062 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8410062 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:8410062 | pubmed:issn | 0022-510X | lld:pubmed |
| pubmed-article:8410062 | pubmed:author | pubmed-author:ChenHH | lld:pubmed |
| pubmed-article:8410062 | pubmed:author | pubmed-author:ChoppMM | lld:pubmed |
| pubmed-article:8410062 | pubmed:author | pubmed-author:ZhangZ GZG | lld:pubmed |
| pubmed-article:8410062 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8410062 | pubmed:volume | 117 | lld:pubmed |
| pubmed-article:8410062 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8410062 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8410062 | pubmed:pagination | 240-4 | lld:pubmed |
| pubmed-article:8410062 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
| pubmed-article:8410062 | pubmed:meshHeading | pubmed-meshheading:8410062-... | lld:pubmed |
| pubmed-article:8410062 | pubmed:meshHeading | pubmed-meshheading:8410062-... | lld:pubmed |
| pubmed-article:8410062 | pubmed:meshHeading | pubmed-meshheading:8410062-... | lld:pubmed |
| pubmed-article:8410062 | pubmed:meshHeading | pubmed-meshheading:8410062-... | lld:pubmed |
| pubmed-article:8410062 | pubmed:meshHeading | pubmed-meshheading:8410062-... | lld:pubmed |
| pubmed-article:8410062 | pubmed:meshHeading | pubmed-meshheading:8410062-... | lld:pubmed |
| pubmed-article:8410062 | pubmed:meshHeading | pubmed-meshheading:8410062-... | lld:pubmed |
| pubmed-article:8410062 | pubmed:meshHeading | pubmed-meshheading:8410062-... | lld:pubmed |
| pubmed-article:8410062 | pubmed:meshHeading | pubmed-meshheading:8410062-... | lld:pubmed |
| pubmed-article:8410062 | pubmed:meshHeading | pubmed-meshheading:8410062-... | lld:pubmed |
| pubmed-article:8410062 | pubmed:meshHeading | pubmed-meshheading:8410062-... | lld:pubmed |
| pubmed-article:8410062 | pubmed:meshHeading | pubmed-meshheading:8410062-... | lld:pubmed |
| pubmed-article:8410062 | pubmed:meshHeading | pubmed-meshheading:8410062-... | lld:pubmed |
| pubmed-article:8410062 | pubmed:meshHeading | pubmed-meshheading:8410062-... | lld:pubmed |
| pubmed-article:8410062 | pubmed:year | 1993 | lld:pubmed |
| pubmed-article:8410062 | pubmed:articleTitle | Duration dependent post-ischemic hypothermia alleviates cortical damage after transient middle cerebral artery occlusion in the rat. | lld:pubmed |
| pubmed-article:8410062 | pubmed:affiliation | Department of Neurology, Henry Ford Hospital, Detroit, MI 48202. | lld:pubmed |
| pubmed-article:8410062 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8410062 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:8410062 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8410062 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8410062 | lld:pubmed |
