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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1993-11-4
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pubmed:abstractText |
In September 1984, the Pediatric Oncology Group began accrual to a Phase I/II study designed to assess the efficacy and toxicity of sequentially escalated doses of hyperfractionated (twice daily) radiotherapy in children with poor-prognosis brain stem tumors. Pediatric Oncology Group Study #8495 closed in June 1990 with a total of 136 patients on study. We report here the outcome of patients treated at the third and final dose level (75.6 Gy), and compare the results to those obtained at the 66 and 70.2 Gy dose levels.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0360-3016
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
30
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
197-206
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:8407392-Adolescent,
pubmed-meshheading:8407392-Adult,
pubmed-meshheading:8407392-Brain Neoplasms,
pubmed-meshheading:8407392-Brain Stem,
pubmed-meshheading:8407392-Child,
pubmed-meshheading:8407392-Child, Preschool,
pubmed-meshheading:8407392-Female,
pubmed-meshheading:8407392-Follow-Up Studies,
pubmed-meshheading:8407392-Glioma,
pubmed-meshheading:8407392-Humans,
pubmed-meshheading:8407392-Magnetic Resonance Imaging,
pubmed-meshheading:8407392-Male,
pubmed-meshheading:8407392-Multivariate Analysis,
pubmed-meshheading:8407392-Prognosis,
pubmed-meshheading:8407392-Radiation Injuries,
pubmed-meshheading:8407392-Radiotherapy Dosage,
pubmed-meshheading:8407392-Steroids
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pubmed:year |
1993
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pubmed:articleTitle |
Final results of a study of escalating doses of hyperfractionated radiotherapy in brain stem tumors in children: a Pediatric Oncology Group study.
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pubmed:affiliation |
McGill University, Montreal, Canada.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Controlled Clinical Trial,
Multicenter Study,
Clinical Trial, Phase II,
Clinical Trial, Phase I
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