Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1993-11-22
pubmed:abstractText
Infection with parvovirus H-1 strongly interfered with the proliferation of non-established tissue cultures derived from human breast tumors, but had little effect on the growth of corresponding normal human mammary cells. Even though tumor cells were always more sensitive to the virus than normal tissue from the same patient, appreciable quantitative differences were observed among tumor specimens. With time and sub-cultures, the killing effect of the virus on tumor cells became amplified. The impaired growth of infected tumor cells was due both to cytotoxic and to cytostatic action of H-1 virus and was associated with their greater capacity for virus-DNA amplification as compared with normal cells.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0020-7136
pubmed:author
pubmed:issnType
Print
pubmed:day
21
pubmed:volume
55
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
672-7
pubmed:dateRevised
2007-7-24
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Parvovirus H-1 inhibits growth of short-term tumor-derived but not normal mammary tissue cultures.
pubmed:affiliation
Laboratory of Biophysics and Radiobiology, Université Libre de Bruxelles, Rhode-St-Genèse, Belgium.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't