Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1977-4-30
pubmed:abstractText
The endogenous transcriptional capacity (RNA polymerase I and II activity) of liver chromatin from chicks treated with 17 beta-estradiol for 24 h (E 24) was double that of the controls. E 24 chromatin contained estradiol receptor activity while control chromatin did not. Its presence suggested an implication in the enhanced activities of RNA polymerases of E 24 chromatin. When semi-purified estradiol receptor was added to control chromatin, the endogenous transcriptional capacity of this chromatin was greatly increased. Studies with alpha-amanitin showed that both RNA polymerase I and II were stimulated by the estradiol receptor. This stimulation was observed as long as homology of the system was maintained. Solubilized homologous RNA polymerases were stimulated much less by the hormone complex in the presence of heterologous DNA than with homologous chromatin. Prokaryotic RNA polymerase could not be stimulated by chick liver estradiol receptor in the presence of heterologous DNA.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/840645-1093165, http://linkedlifedata.com/resource/pubmed/commentcorrection/840645-172899, http://linkedlifedata.com/resource/pubmed/commentcorrection/840645-173720, http://linkedlifedata.com/resource/pubmed/commentcorrection/840645-182542, http://linkedlifedata.com/resource/pubmed/commentcorrection/840645-182691, http://linkedlifedata.com/resource/pubmed/commentcorrection/840645-182692, http://linkedlifedata.com/resource/pubmed/commentcorrection/840645-4332771, http://linkedlifedata.com/resource/pubmed/commentcorrection/840645-4376023, http://linkedlifedata.com/resource/pubmed/commentcorrection/840645-4452362, http://linkedlifedata.com/resource/pubmed/commentcorrection/840645-4458802, http://linkedlifedata.com/resource/pubmed/commentcorrection/840645-4737496, http://linkedlifedata.com/resource/pubmed/commentcorrection/840645-4797637, http://linkedlifedata.com/resource/pubmed/commentcorrection/840645-4855626, http://linkedlifedata.com/resource/pubmed/commentcorrection/840645-5012312, http://linkedlifedata.com/resource/pubmed/commentcorrection/840645-5012469, http://linkedlifedata.com/resource/pubmed/commentcorrection/840645-5069713, http://linkedlifedata.com/resource/pubmed/commentcorrection/840645-5559842, http://linkedlifedata.com/resource/pubmed/commentcorrection/840645-5575170, http://linkedlifedata.com/resource/pubmed/commentcorrection/840645-5761390
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0305-1048
pubmed:author
pubmed:issnType
Print
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
381-95
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
Stimulation of RNA polymerase I and II activities by 17 beta -estradiol receptor on chick liver chromatin.
pubmed:publicationType
Journal Article