|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
1
|
|
pubmed:dateCreated |
1993-10-22
|
|
pubmed:abstractText |
We have constructed a high-resolution genetic linkage map spanning the proximal 32 cM of mouse chromosome 17 including the t complex. Simple sequence repeats at D17Tu1 and D17Mit6 were employed to identify 121 recombinants among 374 offspring of a (C57BL/6 x CAST/Ei) x C57BL/6 backcross. In contrast to previously reported interspecific Mus domesticus x Mus spretus backcrosses, we did not observe inversion polymorphisms with our cross. This and the relatively high frequency of DNA polymorphisms between C57BL/6 and CAST/Ei allowed us to put 32 RFLV markers and 32 PCR markers on a single map. We present the localization of four new DNA markers and determined map positions for 10 other loci, which previously had been assigned to intervals of the t complex only through the study of partial t haplotype chromosomes.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jul
|
|
pubmed:issn |
0888-7543
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
17
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
110-20
|
|
pubmed:dateRevised |
2009-11-19
|
|
pubmed:meshHeading |
pubmed-meshheading:8406442-Animals,
pubmed-meshheading:8406442-Base Sequence,
pubmed-meshheading:8406442-Chromosome Inversion,
pubmed-meshheading:8406442-Chromosome Mapping,
pubmed-meshheading:8406442-Cloning, Molecular,
pubmed-meshheading:8406442-Cricetinae,
pubmed-meshheading:8406442-Cricetulus,
pubmed-meshheading:8406442-Crosses, Genetic,
pubmed-meshheading:8406442-DNA Probes,
pubmed-meshheading:8406442-Genetic Markers,
pubmed-meshheading:8406442-Humans,
pubmed-meshheading:8406442-Hybrid Cells,
pubmed-meshheading:8406442-Hybridization, Genetic,
pubmed-meshheading:8406442-Mice,
pubmed-meshheading:8406442-Mice, Inbred C57BL,
pubmed-meshheading:8406442-Mice, Inbred Strains,
pubmed-meshheading:8406442-Molecular Sequence Data,
pubmed-meshheading:8406442-Muridae,
pubmed-meshheading:8406442-Polymerase Chain Reaction,
pubmed-meshheading:8406442-Species Specificity
|
|
pubmed:year |
1993
|
|
pubmed:articleTitle |
High-resolution comparative mapping of mouse chromosome 17.
|
|
pubmed:affiliation |
Department of Molecular Biology, Princeton University, New Jersey 08544-1014.
|
|
pubmed:publicationType |
Journal Article,
Comparative Study
|
