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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1993-11-4
|
| pubmed:abstractText |
By in situ hybridization with EBER oligonucleotides and immunohistochemistry with anti-latent membrane protein 1 (LMP1) antibody, we compared the detection rate of Epstein-Barr virus (EBV) in Hodgkin's disease and anaplastic large-cell lymphomas in children. Among the 13 cases of Hodgkin's disease tested, 7 (54%) were found to be EBV associated (EBER transcripts +, LMP1 +). None of the 11 cases of ALC lymphomas was found to contain EBV genomes or gene products. This may indicate that EBV is not a pathogenic agent in anaplastic large-cell lymphomas in children in comparison to Hodgkin's disease.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
0309-0167
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
23
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
189-91
|
| pubmed:dateRevised |
2007-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:8406393-Adolescent,
pubmed-meshheading:8406393-Child,
pubmed-meshheading:8406393-Child, Preschool,
pubmed-meshheading:8406393-Herpesvirus 4, Human,
pubmed-meshheading:8406393-Hodgkin Disease,
pubmed-meshheading:8406393-Humans,
pubmed-meshheading:8406393-Immunohistochemistry,
pubmed-meshheading:8406393-In Situ Hybridization,
pubmed-meshheading:8406393-Lymphoma, Large B-Cell, Diffuse,
pubmed-meshheading:8406393-Tumor Virus Infections
|
| pubmed:year |
1993
|
| pubmed:articleTitle |
High incidence of Epstein-Barr virus detection in Hodgkin's disease and absence of detection in anaplastic large-cell lymphoma in children.
|
| pubmed:affiliation |
Laboratoire d'Anatomie Pathologique, Centre Hospitalier Universitaire de Purpan, Toulouse, France.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|