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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
1993-10-28
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pubmed:abstractText |
Cortical blood flow (CoBF) was measured continuously by the laser-Doppler method to evaluate the effect of hypercapnia on cortical blood flow during ten surgical procedures in ten young patients (mean +/- SD 9.3 +/- 6.4 yr) with Moyamoya disease. The CoBF was 42.8 +/- 13.4 (ml.100 g-1.min-1) during normocapnia (PaCO2 = 39.0 +/- 2.4 mmHg), and 38.7 +/- 14.4 during hypercapnia (PaCO2 = 47.1 +/- 2.5 mmHg). There was a decrease in CoBF with hypercapnia (P < 0.05) so that the normal CoBF response to hypercapnia was impaired during surgery in the patients with Moyamoya disease. He concluded that patients with Moyamoya disease have a precarious cerebral circulation and hypercapnia may be detrimental to the cortical circulation. This suggests that normocapnia is preferable to hypercapnia in patients with Moyamoya disease during anaesthesia.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0832-610X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
709-13
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:8403153-Adolescent,
pubmed-meshheading:8403153-Adult,
pubmed-meshheading:8403153-Anastomosis, Surgical,
pubmed-meshheading:8403153-Anesthesia, General,
pubmed-meshheading:8403153-Anesthesia, Inhalation,
pubmed-meshheading:8403153-Anesthesia, Intravenous,
pubmed-meshheading:8403153-Carbon Dioxide,
pubmed-meshheading:8403153-Cerebral Arteries,
pubmed-meshheading:8403153-Cerebrovascular Circulation,
pubmed-meshheading:8403153-Child,
pubmed-meshheading:8403153-Child, Preschool,
pubmed-meshheading:8403153-Female,
pubmed-meshheading:8403153-Humans,
pubmed-meshheading:8403153-Hypercapnia,
pubmed-meshheading:8403153-Laser-Doppler Flowmetry,
pubmed-meshheading:8403153-Male,
pubmed-meshheading:8403153-Moyamoya Disease,
pubmed-meshheading:8403153-Temporal Arteries
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pubmed:year |
1993
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pubmed:articleTitle |
Cortical blood flow response to hypercapnia during anaesthesia in Moyamoya disease.
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pubmed:affiliation |
Department of Anaesthesiology, Osaka Neurological Institute, Japan.
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pubmed:publicationType |
Journal Article
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