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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1993-11-19
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pubmed:abstractText |
Slit-scan flow cytometry provides a method to analyze large numbers of metaphase chromosomes in a relatively short time due to morphological features. The high detection rate requires fast computing for on-line analysis. Up to now, this has been achieved using special-purpose computers, parallel systems or other complex hardware. Here, we describe an algorithm that can be implemented on a general-purpose personal computer. Digitized chromosome profiles can be classified by several criteria especially for the detection of chromosome abnormalities in biological dosimetry. A data set of approximately 4600 profiles was used. Programming in assembler results in an average computing time of about 600 microseconds per profile. Thus on-line evaluation of slit-scanning data appears to become feasible for many flow cytometers running nowadays.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0266-7061
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
381-5
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:8402203-Algorithms,
pubmed-meshheading:8402203-Animals,
pubmed-meshheading:8402203-Chromosomes,
pubmed-meshheading:8402203-Chromosomes, Human,
pubmed-meshheading:8402203-Cricetinae,
pubmed-meshheading:8402203-Cricetulus,
pubmed-meshheading:8402203-Flow Cytometry,
pubmed-meshheading:8402203-Humans,
pubmed-meshheading:8402203-Microcomputers,
pubmed-meshheading:8402203-Online Systems
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pubmed:year |
1993
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pubmed:articleTitle |
Time-optimized analysis of slit-scan chromosome profiles on a general-purpose personal computer.
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pubmed:affiliation |
Institute of Applied Physics, University, Heidelberg, Germany.
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pubmed:publicationType |
Journal Article
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