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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
1993-11-22
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pubmed:abstractText |
To compare extensive with limited lymph node dissection in the surgical treatment of gastric cancer, 320 patients undergoing gastric resection during 1981-1990 were divided into two groups. Although patients undergoing extended lymphadenectomy (n = 157) had a longer operating time (P = 0.0001) and a greater intraoperative blood transfusion requirement (P = 0.009) than those receiving limited dissection (n = 163), the incidence of postoperative complications (22.3 versus 28.2 per cent, P = 0.13) and the hospital mortality rate (3.8 versus 7.4 per cent, P = 0.12) were similar in the two groups. The 5-year survival rate after curative resection (117 and 121 patients after extensive and limited lymph node dissection respectively) was 65.4 versus 50.1 per cent (P = 0.01): 85.9 versus 82.2 per cent for stage I disease (P = 0.60), 66.1 versus 57.8 per cent for stage II (P = 0.82) and 48.7 versus 29.8 per cent for stage III (P = 0.02). Multivariate analysis using the Cox model showed that the extent of lymphadenectomy was an independent prognostic factor for survival (P = 0.01). The results support the value of extensive lymph node dissection in the surgical treatment of gastric carcinoma.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0007-1323
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
80
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1153-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8402119-Adenocarcinoma,
pubmed-meshheading:8402119-Cohort Studies,
pubmed-meshheading:8402119-Female,
pubmed-meshheading:8402119-Gastrectomy,
pubmed-meshheading:8402119-Humans,
pubmed-meshheading:8402119-Lymph Node Excision,
pubmed-meshheading:8402119-Male,
pubmed-meshheading:8402119-Middle Aged,
pubmed-meshheading:8402119-Prognosis,
pubmed-meshheading:8402119-Retrospective Studies,
pubmed-meshheading:8402119-Stomach Neoplasms,
pubmed-meshheading:8402119-Survival Rate,
pubmed-meshheading:8402119-Time Factors
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pubmed:year |
1993
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pubmed:articleTitle |
Extensive versus limited lymph node dissection for gastric cancer: a comparative study of 320 patients.
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pubmed:affiliation |
Istituto di Clinica Chirurgica, Università Cattolica del Sacro Cuore, Rome, Italy.
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pubmed:publicationType |
Journal Article,
Comparative Study
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