Linked Life Data

8401148

Source:http://linkedlifedata.com/resource/pubmed/id/8401148

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1993-10-25
pubmed:abstractText
To test whether repeated HBO exposures would increase activity of skeletal muscle metabolic enzymes, 27 rabbits (3 groups) were exposed 90 min/day, 5 days/wk to either 100% O2 at 243 kPa (HBO), 100% O2 at 101 kPa (HIO), or 21% O2 at 101 kPa (CON). Four animals per group were killed after 2 wk treatment, and the remaining five per group were killed after 8 wk of treatment. Soleus, plantaris, and tibialis anterior muscles were removed, and the activities of adenylate kinase, alpha-glycerophosphate dehydrogenase, and citrate synthase were measured. After 8 wk there was no difference in enzyme activity between groups for either plantaris or tibialis anterior. In the soleus after 8 wk there was no difference between groups in adenylate kinase activity, but alpha-glycerophosphate dehydrogenase activity was 56% greater (P < 0.05) in HBO than in HIO and 50% greater than in CON, and citrate synthase activity in HBO was 24% greater (P < 0.05) than that in HIO and 36% greater than that in CON. Inasmuch as the soleus is a postural muscle, these results suggest that long-term HBO treatments can increase enzyme activity in an actively contracting muscle.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1066-2936
pubmed:author
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
189-96
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Skeletal muscle metabolic enzymes are altered by hyperbaric oxygenation treatments.
pubmed:affiliation
Department of Kinesiology, Louisiana State University, Baton Rouge 70803.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S.