| pubmed-article:8396561 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8396561 | lifeskim:mentions | umls-concept:C0085112 | lld:lifeskim |
| pubmed-article:8396561 | lifeskim:mentions | umls-concept:C0079731 | lld:lifeskim |
| pubmed-article:8396561 | lifeskim:mentions | umls-concept:C0040715 | lld:lifeskim |
| pubmed-article:8396561 | lifeskim:mentions | umls-concept:C1527148 | lld:lifeskim |
| pubmed-article:8396561 | lifeskim:mentions | umls-concept:C0205359 | lld:lifeskim |
| pubmed-article:8396561 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:8396561 | pubmed:dateCreated | 1993-10-8 | lld:pubmed |
| pubmed-article:8396561 | pubmed:abstractText | C.B-17 SCID mice were inoculated with human peripheral blood leukocytes (PBLs) from normal Epstein-Barr virus (EBV)-seropositive and -seronegative donors. Confirmation of a functioning human immune response was demonstrated by the detection of human antibody after inoculation with rotavirus, tetanus toxoid, or EBV. One group of animals inoculated with PBLs from an EBV-seropositive donor developed immunoblastic lymphomas approximately 9 weeks after transplantation. Confirmation of the species and sex of origin of the tumor cells was established using a spontaneous cell line prepared from the tumor. At passage I, the tumor-cell line (AGTI) showed 15% of the metaphases with a translocation involving chromosomes 5 and 14. A lymphoblastoid cell line (AGLCL) established from the same PBLs from the same donor at the time of inoculation of the mice had a normal female karyotype. The AGLCL and a clone of AGTI cells were analyzed for rearrangement of immunoglobulin heavy chain (IgH) genes; both cell lines showed rearrangement of both IgH alleles. The results outlined in this report suggest that a spontaneous chromosomal translocation involving chromosome 14 occurred in normal PBLs in the SCID mouse. | lld:pubmed |
| pubmed-article:8396561 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8396561 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8396561 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8396561 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8396561 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8396561 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8396561 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8396561 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8396561 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8396561 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8396561 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8396561 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:8396561 | pubmed:issn | 0020-7136 | lld:pubmed |
| pubmed-article:8396561 | pubmed:author | pubmed-author:AllenC MCM | lld:pubmed |
| pubmed-article:8396561 | pubmed:author | pubmed-author:GlaserRR | lld:pubmed |
| pubmed-article:8396561 | pubmed:author | pubmed-author:VasquezMM | lld:pubmed |
| pubmed-article:8396561 | pubmed:author | pubmed-author:SheridanJ FJF | lld:pubmed |
| pubmed-article:8396561 | pubmed:author | pubmed-author:BonneauR HRH | lld:pubmed |
| pubmed-article:8396561 | pubmed:author | pubmed-author:TheilK SKS | lld:pubmed |
| pubmed-article:8396561 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8396561 | pubmed:day | 9 | lld:pubmed |
| pubmed-article:8396561 | pubmed:volume | 55 | lld:pubmed |
| pubmed-article:8396561 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8396561 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8396561 | pubmed:pagination | 281-7 | lld:pubmed |
| pubmed-article:8396561 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:8396561 | pubmed:meshHeading | pubmed-meshheading:8396561-... | lld:pubmed |
| pubmed-article:8396561 | pubmed:meshHeading | pubmed-meshheading:8396561-... | lld:pubmed |
| pubmed-article:8396561 | pubmed:meshHeading | pubmed-meshheading:8396561-... | lld:pubmed |
| pubmed-article:8396561 | pubmed:meshHeading | pubmed-meshheading:8396561-... | lld:pubmed |
| pubmed-article:8396561 | pubmed:meshHeading | pubmed-meshheading:8396561-... | lld:pubmed |
| pubmed-article:8396561 | pubmed:meshHeading | pubmed-meshheading:8396561-... | lld:pubmed |
| pubmed-article:8396561 | pubmed:meshHeading | pubmed-meshheading:8396561-... | lld:pubmed |
| pubmed-article:8396561 | pubmed:meshHeading | pubmed-meshheading:8396561-... | lld:pubmed |
| pubmed-article:8396561 | pubmed:meshHeading | pubmed-meshheading:8396561-... | lld:pubmed |
| pubmed-article:8396561 | pubmed:meshHeading | pubmed-meshheading:8396561-... | lld:pubmed |
| pubmed-article:8396561 | pubmed:meshHeading | pubmed-meshheading:8396561-... | lld:pubmed |
| pubmed-article:8396561 | pubmed:meshHeading | pubmed-meshheading:8396561-... | lld:pubmed |
| pubmed-article:8396561 | pubmed:meshHeading | pubmed-meshheading:8396561-... | lld:pubmed |
| pubmed-article:8396561 | pubmed:meshHeading | pubmed-meshheading:8396561-... | lld:pubmed |
| pubmed-article:8396561 | pubmed:meshHeading | pubmed-meshheading:8396561-... | lld:pubmed |
| pubmed-article:8396561 | pubmed:meshHeading | pubmed-meshheading:8396561-... | lld:pubmed |
| pubmed-article:8396561 | pubmed:meshHeading | pubmed-meshheading:8396561-... | lld:pubmed |
| pubmed-article:8396561 | pubmed:meshHeading | pubmed-meshheading:8396561-... | lld:pubmed |
| pubmed-article:8396561 | pubmed:meshHeading | pubmed-meshheading:8396561-... | lld:pubmed |
| pubmed-article:8396561 | pubmed:meshHeading | pubmed-meshheading:8396561-... | lld:pubmed |
| pubmed-article:8396561 | pubmed:year | 1993 | lld:pubmed |
| pubmed-article:8396561 | pubmed:articleTitle | Spontaneous development of a chromosomal translocation 5;14 in an Epstein-Barr-virus-associated B-cell lymphoma in a SCID mouse. | lld:pubmed |
| pubmed-article:8396561 | pubmed:affiliation | Department of Medical Microbiology and Immunology, Ohio State University College of Medicine, Columbus 43210. | lld:pubmed |
| pubmed-article:8396561 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8396561 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8396561 | lld:pubmed |
