rdf:type |
|
lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1993-10-8
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pubmed:databankReference |
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pubmed:abstractText |
The amino acid sequence of a rat opioid receptor, designated as ROR-D, has been deduced by cloning and sequencing the cDNA. The ROR-D expressed from the cDNA exhibits high affinities for ligands selective for the opioid receptor kappa-subtype and low affinities for ligands selective for the delta- and mu-subtypes. RNA blot hybridization analysis indicated that ROR-D mRNA is distributed in cerebrum and brainstem but not in cerebellum.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/DNA,
http://linkedlifedata.com/resource/pubmed/chemical/Ligands,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Opioid, delta,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Opioid, kappa,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Opioid, mu
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
|
pubmed:issn |
0014-5793
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:day |
6
|
pubmed:volume |
330
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
77-80
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8396539-Amino Acid Sequence,
pubmed-meshheading:8396539-Animals,
pubmed-meshheading:8396539-Brain,
pubmed-meshheading:8396539-Cells, Cultured,
pubmed-meshheading:8396539-Cloning, Molecular,
pubmed-meshheading:8396539-DNA,
pubmed-meshheading:8396539-Ligands,
pubmed-meshheading:8396539-Molecular Sequence Data,
pubmed-meshheading:8396539-Rats,
pubmed-meshheading:8396539-Rats, Wistar,
pubmed-meshheading:8396539-Receptors, Opioid, delta,
pubmed-meshheading:8396539-Receptors, Opioid, kappa,
pubmed-meshheading:8396539-Receptors, Opioid, mu,
pubmed-meshheading:8396539-Sequence Homology, Amino Acid
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pubmed:year |
1993
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pubmed:articleTitle |
cDNA cloning and pharmacological characterization of an opioid receptor with high affinities for kappa-subtype-selective ligands.
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pubmed:affiliation |
International Institute for Advanced Studies, Kyoto, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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