Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1993-10-5
pubmed:abstractText
A series of herpes simplex viruses type 1 (HSV-1) neutralizing monoclonal antibodies (mAbs) with different plaque development inhibition (PDI) activity were tested for passive protection in mice. When virus was inoculated intracranially, mAbs with PDI activity were not more protective than mAbs without PDI activity. However, when virus was inoculated percutaneously, there was a trend indicating that neutralizing mAbs with PDI power were more active in protecting mice from the cutaneous lesion than mAbs without PDI power. The results are discussed in relation to the possible involvement of PDI activity in in vivo protection and to the fact that this mechanism of protection might operate in cutaneous, but not in nervous tissue.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1121-7138
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
205-13
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Passive immune protection by herpes simplex virus-specific monoclonal antibodies with different plaque development inhibition activity.
pubmed:affiliation
Department of Experimental Pathology, University of Bologna, Italy.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't