Linked Life Data

8395040

Source:http://linkedlifedata.com/resource/pubmed/id/8395040

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1993-9-21
pubmed:abstractText
Specific immunoglobulin G (IgG), IgA and IgM antibody titres to Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans were measured by enzyme-linked immunosorbent assay in serum and gingival crevicular fluid at 5 sites in each of 20 chronic periodontitis patients. Specific serum antibody titres correlated with mean gingival crevicular fluid titres. The 3 immunoglobulin subclass responses (IgA, IgG and IgM) to P. gingivalis correlated. A comparison of sites with probing depth < 4 mm and > or = 4 mm showed that the latter group had significantly lower gingival crevicular fluid IgG titres to P. gingivalis. Sites with a gingival index of 3 had significantly lower gingival crevicular fluid IgG titres to this organism than those with a gingival index of less than 3. These findings support the concept that the humoral immune response is protective, as chronic periodontitis patients with greater pocket depths and more gingival inflammation had paradoxically lower antibody titres to suspected periodontopathogens.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
D
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0902-0055
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
65-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Local and systemic antibody response to putative periodontopathogens in patients with chronic periodontitis: correlation with clinical indices.
pubmed:affiliation
Department of Oral Medicine and Pathology, Glasgow Dental Hospital and School, Scotland, United Kingdom.
pubmed:publicationType
Journal Article, Comparative Study