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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
|
pubmed:dateCreated |
1993-9-10
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pubmed:abstractText |
Serum levels of interleukin-2 receptor (IL2R) were determined in children with newly diagnosed Hodgkin disease (n = 68), Wilms tumor (n = 20), osteosarcoma (n = 18), rhabdomyosarcoma (n = 18), or Ewing sarcoma (n = 15). Measurements of soluble IL2R were positively correlated with disease stage in Hodgkin disease but not in other tumors. Very high levels of soluble IL2R (> or = 5000 U/ml) were significantly associated with a poorer treatment outcome in Hodgkin disease (p = 0.006) and retained significance in a multivariate analysis (p = 0.03). The addition of soluble IL2R measurements to existing prognostic models may improve risk assignment in children with Hodgkin disease.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
|
pubmed:issn |
0887-6924
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1242-4
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:8394483-Child,
pubmed-meshheading:8394483-Hodgkin Disease,
pubmed-meshheading:8394483-Humans,
pubmed-meshheading:8394483-Kidney Neoplasms,
pubmed-meshheading:8394483-Multivariate Analysis,
pubmed-meshheading:8394483-Neoplasm Staging,
pubmed-meshheading:8394483-Neoplasms,
pubmed-meshheading:8394483-Osteosarcoma,
pubmed-meshheading:8394483-Prognosis,
pubmed-meshheading:8394483-Receptors, Interleukin-2,
pubmed-meshheading:8394483-Regression Analysis,
pubmed-meshheading:8394483-Rhabdomyosarcoma,
pubmed-meshheading:8394483-Sarcoma, Ewing,
pubmed-meshheading:8394483-Solubility,
pubmed-meshheading:8394483-Wilms Tumor
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pubmed:year |
1993
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pubmed:articleTitle |
Serum interleukin-2 receptor levels in Hodgkin disease and other solid tumors of childhood.
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pubmed:affiliation |
Department of Hematology-Oncology, St Jude Children's Research Hospital, Memphis, TN 38101.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|