Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1993-8-30
pubmed:abstractText
We reviewed a series of 194 lung opacities presumed to be bronchogenic carcinomas occurring either simultaneously with (n = 46) or metachronously to (n = 148) a head and neck cancer. The purpose of the study was to evaluate the operative mortality and morbidity and to assess with a survival analysis whether the lung lesions actually were primary carcinomas or metastases of the head and neck cancer. Operation was contraindicated in 77 patients: 36 for metastatic spread, 5 for small-cell carcinoma, and 35 for respiratory insufficiency. The remaining 118 underwent operation: lobectomy for 82, pneumonectomy for 30, wedge resection for 1, and exploratory thoracotomy for 5. The operative mortality was 5%, and the nonfatal morbidity was 22%. The survival at 5 years for patients who underwent operation for bronchogenic cancer was 19.7% (27.2% for stage I, 19% for stage II, 4.5% for stage IIIA, and 0% for stage IIIB). The survival of these patients was not significantly different with respect to the synchronous or metachronous occurrence or the histologic classification (squamous or non-squamous). We conclude that, despite the poor survival, several of these lung lesions associated with a head and neck cancer were most likely a primary bronchogenic cancer. Surgical management is justified because of the observed postoperative mortality.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0022-5223
pubmed:author
pubmed:issnType
Print
pubmed:volume
106
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
218-27
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed-meshheading:8393506-Adult, pubmed-meshheading:8393506-Aged, pubmed-meshheading:8393506-Aged, 80 and over, pubmed-meshheading:8393506-Bone Neoplasms, pubmed-meshheading:8393506-Carcinoma, Bronchogenic, pubmed-meshheading:8393506-Carcinoma, Small Cell, pubmed-meshheading:8393506-Carcinoma, Squamous Cell, pubmed-meshheading:8393506-Combined Modality Therapy, pubmed-meshheading:8393506-Female, pubmed-meshheading:8393506-Follow-Up Studies, pubmed-meshheading:8393506-Head and Neck Neoplasms, pubmed-meshheading:8393506-Humans, pubmed-meshheading:8393506-Lung Neoplasms, pubmed-meshheading:8393506-Male, pubmed-meshheading:8393506-Middle Aged, pubmed-meshheading:8393506-Neoplasm Staging, pubmed-meshheading:8393506-Neoplasms, Multiple Primary, pubmed-meshheading:8393506-Postoperative Complications, pubmed-meshheading:8393506-Survival Rate
pubmed:year
1993
pubmed:articleTitle
Bronchogenic cancer associated with head and neck tumors. Survival analysis of 194 patients.
pubmed:affiliation
Service de Chirurgie Thoracique, Hospices Civils, Strasbourg, France.
pubmed:publicationType
Journal Article