Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1993-8-26
pubmed:abstractText
The effect of male rat sexual behavior on the binding of [3H]-flunitrazepam (FNP) in frontal cortex, hypothalamus and hippocampus was measured. The groups included were: (A) control (no sexual experience) handled males; (B) male rats sacrificed 24 h after their fifth mating experience; (C) males sacrificed 48 h after their fifth mating experience; (D) male rats sacrificed after 5 intromissions during the sixth mating experience; and (E) males sacrificed immediately after the ejaculation during the sixth mating experience. Relative to handled controls, significant decreases in maximal [3H]-FNP binding (Bmax) were observed in frontal cortex and hippocampus of animals sacrificed after 5 intromissions and in frontal cortex of rats sacrificed 24 h after the last mating experience. Relative to males sacrificed after 5 intromissions, males sacrificed immediately after ejaculation exhibited a rapid increase in Bmax in frontal cortex and hippocampus. No between-group differences in Kd for [3H]-FNP were noted, and sexual experience had no effect on the Bmax of [3H]-FNP in the hypothalamus.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
21
pubmed:volume
611
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
326-9
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Male rat sexual behavior induces changes in [3H]flunitrazepam binding.
pubmed:affiliation
Division de Investigaciones en Neurociencias, Instituto Mexicano de Psiquiatria, CINVESTAV, IPN, D.F.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't