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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1977-4-25
pubmed:abstractText
The structural polypeptides of five bunyaviruses, snowshoe hare, Lumbo and La Crosse viruses (members of the California encephalitis subgroup of bunyaviruses), Bunyamwera and Main Drain viruses (members of the Bunyamwera subgroup of bunyaviruses), have been compared by polyacrylamide-SDS gel electrophoresis. Each virus was found to possess three major structural polypeptides, two glycoproteins (G1 and G2), and one nucleocapsid protein (N). Although the sizes of the G1 polypeptides (mol. wt. approx. 115 X 10(3)) and G2 polypeptides (mol. wt. approx. 38 X 10(3)) of the five viruses were found to be essentially similar, the sizes of the N polypeptides of the various viruses differed (mol. wt. range 19 to 24 X 10(3)). The RNA genomes of four bunyaviruses (snowshoe hare, La Crosse, Bunyamwera and Main Drain) have also been compared. Each virus has three RNA species of mol. wt. approx. 3 X 10(6), 1-9 X 10(6) and 0-4 X 10(6). Minor size differences were observed for the smallest RNA species of the four viruses (mol. wt. range 0-34 to 0-50 X 10(6)). For snowshoe hare virus the RNA segments hav a 5' sequence of pppAp...which suggests that the RNA is linear and not circular.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0022-1317
pubmed:author
pubmed:issnType
Print
pubmed:volume
34
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
257-68
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
The virus particle nucleic acids and proteins of four bunyaviruses.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S.