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rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0007590,
umls-concept:C0018956,
umls-concept:C0033684,
umls-concept:C0043393,
umls-concept:C0079429,
umls-concept:C0162610,
umls-concept:C0259902,
umls-concept:C0449243,
umls-concept:C0699819,
umls-concept:C0719517,
umls-concept:C0812269,
umls-concept:C0949374,
umls-concept:C1321889,
umls-concept:C1514873,
umls-concept:C1546857,
umls-concept:C1556066,
umls-concept:C1619636,
umls-concept:C2348205,
umls-concept:C2349182,
umls-concept:C2700640
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|
pubmed:issue |
3
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|
pubmed:dateCreated |
1993-7-28
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|
pubmed:databankReference |
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pubmed:abstractText |
The emb-5 gene is required for the correct timing of division of gut precursor cells during gastrulation in Caenorhabditis elegans. We have now characterized the molecular structure of emb-5. The predicted emb-5-encoded protein (EMB-5) possesses an extremely acidic amino-terminus and overall similarity to the Saccharomyces cerevisiae nuclear protein SPT6, which has been shown to affect the transcription of a variety of genes and suggested to play a role in chromatin assembly or modification. EMB-5 may function in the control of cell cycle timing by modulating chromatin structure and consequently affects morphogenesis of C. elegans.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0026-8925
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
239
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pubmed:geneSymbol |
emb-5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
313-22
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:8391108-Amino Acid Sequence,
pubmed-meshheading:8391108-Animals,
pubmed-meshheading:8391108-Base Sequence,
pubmed-meshheading:8391108-Caenorhabditis elegans,
pubmed-meshheading:8391108-Cell Division,
pubmed-meshheading:8391108-Chromosome Mapping,
pubmed-meshheading:8391108-Chromosome Walking,
pubmed-meshheading:8391108-DNA Mutational Analysis,
pubmed-meshheading:8391108-DNA Transposable Elements,
pubmed-meshheading:8391108-Female,
pubmed-meshheading:8391108-Fungal Proteins,
pubmed-meshheading:8391108-Gastrula,
pubmed-meshheading:8391108-Genes, Fungal,
pubmed-meshheading:8391108-Genes, Helminth,
pubmed-meshheading:8391108-Helminth Proteins,
pubmed-meshheading:8391108-Intestines,
pubmed-meshheading:8391108-Male,
pubmed-meshheading:8391108-Molecular Sequence Data,
pubmed-meshheading:8391108-Morphogenesis,
pubmed-meshheading:8391108-Nuclear Proteins,
pubmed-meshheading:8391108-Saccharomyces cerevisiae,
pubmed-meshheading:8391108-Saccharomyces cerevisiae Proteins,
pubmed-meshheading:8391108-Transcription Factors,
pubmed-meshheading:8391108-Transcriptional Elongation Factors,
pubmed-meshheading:8391108-Transformation, Genetic
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pubmed:year |
1993
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pubmed:articleTitle |
emb-5, a gene required for the correct timing of gut precursor cell division during gastrulation in Caenorhabditis elegans, encodes a protein similar to the yeast nuclear protein SPT6.
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|
pubmed:affiliation |
Fundamental Research Laboratories, NEC Corporation, Tsukuba, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study
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