Linked Life Data

8389218

Source:http://linkedlifedata.com/resource/pubmed/id/8389218

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1993-7-2
pubmed:abstractText
Shigellae are the most frequently isolated invasive bacteria in Djibouti. 140 clinical strains collected during an eight months period have been studied for their in vitro susceptibility to antibiotics mainly used in treatment and prophylaxis by measure of MIC (agar dilution) for all antibiotics except for trimethoprim-sulfamethoxazole, trimethoprim and sulfamethoxazole (disk diffusion on lysed horse blood medium). Characterization of beta-lactamase is carried out for all strains resistant to amoxicillin and for all S. sonnei. The overall prevalence of resistance to amoxicillin is 41.7% (penicillinase TEM-1, OXA-1 and OXA-3 alone or associated) to tetracyclines 97.1% and to trimethoprim-sulfamethoxazole 51.4%. This prevalence is particularly high for amoxicillin with S. flexneri and for trimethoprim-sulfamethoxazole with S. sonnei. All strains of S. sonnei have a low level chromosomal cephalosporinase without phenotypic expression. Among 68 strains sensitive to trimethoprim-sulfamethoxazole, 39 are resistant to sulfamethoxazole alone. All strains are sensitive to nalidixic acid and fluoroquinolones. These data allows us to recommend fluoroquinolones for treatment and prophylaxis of shigellosis in Djibouti.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0037-9085
pubmed:author
pubmed:issnType
Print
pubmed:volume
86
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
35-40
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
[Antibiotic sensitivity of 140 strains of Shigella isolated in Djibouti].
pubmed:affiliation
Service de Biologie médicale, HIA Bégin, Saint-Mandé.
pubmed:publicationType
Journal Article, English Abstract