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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
1993-6-21
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pubmed:abstractText |
The latency-associated transcription unit has been shown to be important for in vivo reactivation of herpes simplex virus from the latent state. A recombinant virus was constructed to alter the largest open reading frame in this region. This virus had a wild-type reactivation phenotype, suggesting that herpes simplex virus does not require a protein function from this reading frame for efficient reactivation from latency.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/8388517-1312626,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8388517-1662697,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8388517-1846963,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8388517-1850005,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8388517-1850045,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8388517-2152989,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8388517-2161947,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8388517-2434993,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8388517-2451758,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8388517-2474674,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8388517-2535901,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8388517-2536101,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8388517-2542019,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8388517-2542601,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8388517-2552271,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8388517-2824816,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8388517-2824818,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8388517-2831380,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8388517-2842950,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8388517-2845123,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8388517-2846871,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8388517-2848928,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8388517-3005980,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8388517-3033640,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8388517-4328483,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8388517-6330452
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0022-538X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
67
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3653-5
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:8388517-DNA, Recombinant,
pubmed-meshheading:8388517-DNA, Viral,
pubmed-meshheading:8388517-Mutagenesis, Insertional,
pubmed-meshheading:8388517-Open Reading Frames,
pubmed-meshheading:8388517-Simplexvirus,
pubmed-meshheading:8388517-Transcription, Genetic,
pubmed-meshheading:8388517-Virus Activation
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pubmed:year |
1993
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pubmed:articleTitle |
The herpes simplex virus type 1 reactivation function lies outside the latency-associated transcript open reading frame ORF-2.
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pubmed:affiliation |
Molecular Biology Institute, School of Medicine, University of California, Los Angeles 90024.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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