| pubmed-article:838662 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:838662 | lifeskim:mentions | umls-concept:C0205474 | lld:lifeskim |
| pubmed-article:838662 | lifeskim:mentions | umls-concept:C1280551 | lld:lifeskim |
| pubmed-article:838662 | lifeskim:mentions | umls-concept:C0018787 | lld:lifeskim |
| pubmed-article:838662 | lifeskim:mentions | umls-concept:C0542341 | lld:lifeskim |
| pubmed-article:838662 | lifeskim:mentions | umls-concept:C1707391 | lld:lifeskim |
| pubmed-article:838662 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:838662 | pubmed:dateCreated | 1977-4-30 | lld:pubmed |
| pubmed-article:838662 | pubmed:abstractText | Mitochondria and sarcoplasmic reticulum (SR) fractions were isolated from exercised-trained (E-T) and sedentary control dog hearts. Measurements of mitochondrial respiratory functions indicated no changes in energy-producing (ATP synthesis) capacity in mitochondria from E-T compared to control dog hearts. However, the ability of isolated mitochondria from E-T hearts to retain accumulated calcium was markedly decreased compared to controls. Inhibition of mitochondrial rates of calcium uptake with the inhibitor, ruthenium red, revealed fewer binding and/or transport sites in mitochondrial membranes from exercised-trained heart preparations. ATP-dependent binding (- oxalate) and uptake (+ oxalate) of calcium by SR preparations from E-T hearts were unchanged compared to controls. In contrast, significant differences in the rates of release of bound calcium were found in SR isolated from E-T hearts. Total myocardial protein, nucleic acids, and connective tissue levels were unchanged in E-T hearts compared to controls. The results suggest subtle changes are occurring in the energy-utilizing mechanism(s) involving calcium transport of the myocardial cell during exercise training. These changes may be related to alterations in the performance of the exercised-trained heart. | lld:pubmed |
| pubmed-article:838662 | pubmed:language | eng | lld:pubmed |
| pubmed-article:838662 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:838662 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:838662 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:838662 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:838662 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:838662 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:838662 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:838662 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:838662 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:838662 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:838662 | pubmed:issn | 0161-7567 | lld:pubmed |
| pubmed-article:838662 | pubmed:author | pubmed-author:DowellR TRT | lld:pubmed |
| pubmed-article:838662 | pubmed:author | pubmed-author:StoneH LHL | lld:pubmed |
| pubmed-article:838662 | pubmed:author | pubmed-author:SordahlL ALA | lld:pubmed |
| pubmed-article:838662 | pubmed:author | pubmed-author:AsimakisG KGK | lld:pubmed |
| pubmed-article:838662 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:838662 | pubmed:volume | 42 | lld:pubmed |
| pubmed-article:838662 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:838662 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:838662 | pubmed:pagination | 426-31 | lld:pubmed |
| pubmed-article:838662 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:838662 | pubmed:meshHeading | pubmed-meshheading:838662-A... | lld:pubmed |
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| pubmed-article:838662 | pubmed:meshHeading | pubmed-meshheading:838662-R... | lld:pubmed |
| pubmed-article:838662 | pubmed:year | 1977 | lld:pubmed |
| pubmed-article:838662 | pubmed:articleTitle | Functions of selected biochemical systems from the exercised-trained dog heart. | lld:pubmed |
| pubmed-article:838662 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:838662 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
