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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1976-10-29
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pubmed:abstractText |
Placement of two 1 cm copper (Cu) coils around the mid-region of each oviduct in a group of five female rabbits with proven fertility, 34 days before mating, virtually prevented fetal implantation in these animals. The oviducts remained patent during a 47 day implantation period and following removal of the Cu coils, does that were remated became pregnant. In two of these does an implantation rate (living fetuses/corpora lutea) of 33% (7/21) was observed and one post-Cu implanted doe had a litter of two. Among four does bearing a single Cu coil on their left oviduct for 28 days prior to mating there was 19% (4/21) implantation of the left side and 56.3% (9/16) on the untreated right side, suggesting a local action by the metal. The results indicate that Cu is an effective anti-fertility agent when implanted around the oviducts and, as a corollary, it is apparent that the metal is not restricted to placement in the uterus in order to prevent pregnancy in rabbits. Non-occluding Cu containing devices may offer a new approach to reversible fertility control in the female that merits further investigation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0020-725X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
123-6
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:8385-Animals,
pubmed-meshheading:8385-Contraceptive Devices, Female,
pubmed-meshheading:8385-Copper,
pubmed-meshheading:8385-Embryo Implantation,
pubmed-meshheading:8385-Fallopian Tubes,
pubmed-meshheading:8385-Female,
pubmed-meshheading:8385-Fertility,
pubmed-meshheading:8385-Pregnancy,
pubmed-meshheading:8385-Pregnancy, Animal,
pubmed-meshheading:8385-Rabbits
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pubmed:year |
1976
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pubmed:articleTitle |
Reversible anti-fertility effect by non-occluding oviductal copper coils in the rabbit.
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pubmed:publicationType |
Journal Article
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