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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1993-4-27
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pubmed:abstractText |
A total of 51 patients with acute exacerbation of chronic bronchitis and pneumonia were enrolled: 27 treated with azithromycin (500 mg once a day for 3 days), and 24 with roxithromycin (150 mg every 12 hours for 7 days). The two regimens were equally effective, with clinical cure in 80% and 72% of patients respectively. Bacteriological eradication on day 19-23 was obtained in 7/11 cases (64%) and in 6/13 cases (46%) in the two groups, respectively. No side effects occurred in patients treated with azithromycin, while they occurred in the roxithromycin group (2 vomiting and 1 gastritis). Clinical and bacteriological efficacy, excellent tolerability, simplified dosage (single daily dose) and short-course (3 days) therapeutic regimen make azithromycin, in our experience, efficacious for the treatment of acute exacerbation of chronic bronchitis and community-acquired pneumonia.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1120-009X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
32-6
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pubmed:dateRevised |
2009-8-4
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pubmed:meshHeading |
pubmed-meshheading:8384658-Adolescent,
pubmed-meshheading:8384658-Adult,
pubmed-meshheading:8384658-Aged,
pubmed-meshheading:8384658-Aged, 80 and over,
pubmed-meshheading:8384658-Azithromycin,
pubmed-meshheading:8384658-Bacterial Infections,
pubmed-meshheading:8384658-Bronchitis,
pubmed-meshheading:8384658-Chronic Disease,
pubmed-meshheading:8384658-Drug Administration Schedule,
pubmed-meshheading:8384658-Erythromycin,
pubmed-meshheading:8384658-Female,
pubmed-meshheading:8384658-Humans,
pubmed-meshheading:8384658-Male,
pubmed-meshheading:8384658-Middle Aged,
pubmed-meshheading:8384658-Pneumonia,
pubmed-meshheading:8384658-Prospective Studies,
pubmed-meshheading:8384658-Roxithromycin,
pubmed-meshheading:8384658-Treatment Outcome
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pubmed:year |
1993
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pubmed:articleTitle |
Clinical efficacy of azithromycin in lower respiratory tract infections.
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pubmed:affiliation |
Pneumology Division, Ospedale Maggiore, USSL 25, Verona, Italy.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial
|