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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
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pubmed:dateCreated |
1993-4-16
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pubmed:databankReference | |
pubmed:abstractText |
Plasmid pIP173, isolated from Salmonella ordonez strain BM2000, confers resistance to tetracycline and a number of other antibiotics. We determined the nucleotide sequence of the pIP173 tetR repressor and tetA resistance genes. The pIP173 tetR gene is essentially identical to the class D tetR gene from plasmid RA1. The pIP173 tet genes are flanked by directly repeated copies of the insertion sequence IS26. Interestingly, the 3' end of the tetR gene, encoding the C-terminal 16 amino acids of the TetR protein, extends into the flanking IS26 sequence. The relationships between the class A, B, C, and D TetA sequences parallel the relationships between the corresponding TetR sequences; class D is more closely related to class B than to either class A or C. Overall, the four TetA sequences show 38% identity and 57% similarity.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0026-8925
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
237
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
301-5
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:8384294-Amino Acid Sequence,
pubmed-meshheading:8384294-Base Sequence,
pubmed-meshheading:8384294-Chromosome Mapping,
pubmed-meshheading:8384294-DNA Transposable Elements,
pubmed-meshheading:8384294-Genes, Bacterial,
pubmed-meshheading:8384294-Molecular Sequence Data,
pubmed-meshheading:8384294-Plasmids,
pubmed-meshheading:8384294-R Factors,
pubmed-meshheading:8384294-Repressor Proteins,
pubmed-meshheading:8384294-Salmonella,
pubmed-meshheading:8384294-Sequence Homology, Amino Acid,
pubmed-meshheading:8384294-Tetracycline Resistance
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pubmed:year |
1993
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pubmed:articleTitle |
Nucleotide sequence of class D tetracycline resistance genes from Salmonella ordonez.
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pubmed:affiliation |
Department of Microbiology, Washington State University, Pullman 99164.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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