rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
2
|
pubmed:dateCreated |
1993-3-9
|
pubmed:abstractText |
Complete functional deficiency of the phagocytic cell enzyme, myeloperoxidase, is described in a patient with rheumatoid arthritis. Measurement of oxygenation and free radical activity by blood monocytes and polymorphonuclear leucocytes shows gross reduction in myeloperoxidase-dependent chemiluminescence. Implications of these data for theories linking reactive oxygen species to inflammatory tissue damage in rheumatoid arthritis are discussed.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0263-7103
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
32
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
162-5
|
pubmed:dateRevised |
2011-11-17
|
pubmed:meshHeading |
pubmed-meshheading:8381323-Adult,
pubmed-meshheading:8381323-Antibodies, Monoclonal,
pubmed-meshheading:8381323-Arthritis, Rheumatoid,
pubmed-meshheading:8381323-Enzyme Activation,
pubmed-meshheading:8381323-Female,
pubmed-meshheading:8381323-Free Radicals,
pubmed-meshheading:8381323-Humans,
pubmed-meshheading:8381323-Luminescent Measurements,
pubmed-meshheading:8381323-Monocytes,
pubmed-meshheading:8381323-Neutrophils,
pubmed-meshheading:8381323-Oxidation-Reduction,
pubmed-meshheading:8381323-Peroxidase,
pubmed-meshheading:8381323-Phagocytes,
pubmed-meshheading:8381323-Superoxides
|
pubmed:year |
1993
|
pubmed:articleTitle |
Myeloperoxidase deficiency in a patient with rheumatoid arthritis: oxygenation and radical activity by phagocytic cells.
|
pubmed:affiliation |
Department of Medicine (Rheumatology), School of Clinical Medicine, Queen's University, Belfast.
|
pubmed:publicationType |
Journal Article,
Case Reports
|