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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
7
|
| pubmed:dateCreated |
1993-10-19
|
| pubmed:abstractText |
Four complex flavanones, kurziflavolactones A [2], B [3], C [4], and D [5] and a complex chalcone 6 with an unprecedented carbon side chain on the flavanone or chalcone A ring have been isolated from a Malaysian plant, Cryptocarya kurzii (Lauraceae). Their structures were determined by extensive spectroscopic analysis, especially 2D nmr experiments. Compounds 3 and 6 showed slight cytotoxicity against KB cells, with IC50 values of 4 and 15 micrograms/ml, respectively. A biosynthetic pathway for the formation of these compounds is suggested.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
0163-3864
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
56
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1153-63
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:8377019-Antineoplastic Agents, Phytogenic,
pubmed-meshheading:8377019-Chalcone,
pubmed-meshheading:8377019-Drug Screening Assays, Antitumor,
pubmed-meshheading:8377019-Flavonoids,
pubmed-meshheading:8377019-Humans,
pubmed-meshheading:8377019-KB Cells,
pubmed-meshheading:8377019-Magnetic Resonance Spectroscopy,
pubmed-meshheading:8377019-Malaysia,
pubmed-meshheading:8377019-Plants, Medicinal
|
| pubmed:year |
1993
|
| pubmed:articleTitle |
Flavonone and chalcone derivatives from Cryptocarya kurzii.
|
| pubmed:affiliation |
Institut de Chimie des Substances Naturelles, C.N.R.S., Gif-sur- Yvette, France.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|