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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
7
|
| pubmed:dateCreated |
1993-10-19
|
| pubmed:abstractText |
A new C31 lanostane-type triterpene, assigned the trivial name suberosol [1], has been isolated from Polyalthia suberosa as an anti-HIV principle. The structure has been characterized as 24-methylenelanost-7,9(11)-diene-3 beta, 15 alpha-diol (suberosol) [1], based on spectroscopic evidence. Compound 1 was found to show anti-HIV replication activity in H9 lymphocyte cells with an EC50 of 3 micrograms/ml.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
0163-3864
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
56
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1130-3
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:8377018-Antiviral Agents,
pubmed-meshheading:8377018-Cells, Cultured,
pubmed-meshheading:8377018-HIV Core Protein p24,
pubmed-meshheading:8377018-HIV-1,
pubmed-meshheading:8377018-Humans,
pubmed-meshheading:8377018-Lymphocytes,
pubmed-meshheading:8377018-Magnetic Resonance Spectroscopy,
pubmed-meshheading:8377018-Plants, Medicinal,
pubmed-meshheading:8377018-Steroids
|
| pubmed:year |
1993
|
| pubmed:articleTitle |
Anti-AIDS agents, 9. Suberosol, a new C31 lanostane-type triterpene and anti-HIV principle from Polyalthia suberosa.
|
| pubmed:affiliation |
Natural Products Laboratory, School of Pharmacy, University of North Carolina, Chapel Hill 27599.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|