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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1993-10-21
|
| pubmed:abstractText |
Cytogenetic study of 14 thyroid nodular hyperplasias revealed a hyperdiploid karyotype in two cases (14%) and a normal chromosomal complement in the remaining cases. Some of the numerical alterations found were identical to the ones considered characteristic of a subset of thyroid adenomas (+5, +7, +9, +12, +14, and +16). Our findings suggest that the cytogenetic events involved in the pathogenesis of thyroid hyperplastic lesions and benign tumors may be closely related, which supports the hypothesis of a biologic "continuum" between these two types of lesions.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
0165-4608
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
69
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
31-4
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:8374896-Adult,
pubmed-meshheading:8374896-Aged,
pubmed-meshheading:8374896-Culture Techniques,
pubmed-meshheading:8374896-Female,
pubmed-meshheading:8374896-Goiter, Nodular,
pubmed-meshheading:8374896-Humans,
pubmed-meshheading:8374896-Hyperplasia,
pubmed-meshheading:8374896-Karyotyping,
pubmed-meshheading:8374896-Male,
pubmed-meshheading:8374896-Middle Aged
|
| pubmed:year |
1993
|
| pubmed:articleTitle |
Thyroid nodular hyperplasia: chromosomal studies in 14 cases.
|
| pubmed:affiliation |
Institute for Molecular Pathology and Immunology, University of Porto--IPATIMUP, Portugal.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|