Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:dateCreated |
1993-10-7
|
| pubmed:abstractText |
Cell surface adhesive glycoproteins are principal regulators of nearly all aspects of immune/inflammatory responses. Using monoclonal antibodies to individual adhesion molecules, the expression and contribution of specific molecules in the pathogenesis of allergen-induced airway hyperresponsiveness in monkeys has been deciphered. Results confirm the importance of cell adhesion and demonstrate that antagonism of a single adhesion molecule may provide a novel therapeutic approach.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0379-0363
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
43
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
151-62
|
| pubmed:dateRevised |
2007-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:8368159-Animals,
pubmed-meshheading:8368159-Antibodies, Monoclonal,
pubmed-meshheading:8368159-Asthma,
pubmed-meshheading:8368159-Cell Adhesion Molecules,
pubmed-meshheading:8368159-Disease Models, Animal,
pubmed-meshheading:8368159-Humans,
pubmed-meshheading:8368159-Inflammation,
pubmed-meshheading:8368159-Monkey Diseases,
pubmed-meshheading:8368159-Primates,
pubmed-meshheading:8368159-Terminology as Topic
|
| pubmed:year |
1993
|
| pubmed:articleTitle |
Efficacy of monoclonal antibodies against adhesion molecules in animal models of asthma.
|
| pubmed:affiliation |
Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT 06877.
|
| pubmed:publicationType |
Journal Article,
Review
|