Linked Life Data

8367768

Source:http://linkedlifedata.com/resource/pubmed/id/8367768

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1993-10-5
pubmed:abstractText
Bone graft subsidence is a serious complication of interbody spinal fusion. In this study, 66 mechanical tests were performed on 35 thoracic vertebral bodies to investigate the in situ mechanics of interbody spinal fusion. The relationships among trabecular bone density, bone strength, and size of bone graft area were analyzed. All vertebral bodies were scanned by quantitative computer tomography (QCT) to determine their bone density before mechanical testing. The decorticated trabecular beds of the vertebral bodies, void of all posterior elements, were loaded in a manner similar to that which occurs after surgical interbody fusion. That is, rectangular blocks of polymethylmethacrylate, representing bone grafts, were used to transfer controlled compressive loads to the decorticated vertebral trabecular surface. Both destructive and nondestructive tests were performed. The relationship between QCT bone density and trabecular bone strength was related by a power function, and, on average, the bone density and trabecular bone strength were 0.137 g/cm3 and 3.97 MPa, respectively. Eighty percent of the vertebral bodies with graft covering 25% of the total end plate area or less failed at loads less than 600 N, while 88% of the vertebral bodies with 30% or greater covered were able to carry a load greater than 600 N. The results suggest that the intrinsic behavior of trabecular bone loaded within the vertebral body is little different from the behavior of the whole body, that QCT bone density is indicative of bone strength, and that interbody graft area should be significantly greater than 30% of the total end plate area to provide a margin of safety.(ABSTRACT TRUNCATED AT 250 WORDS)
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0362-2436
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1011-5
pubmed:dateRevised
2009-7-9
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Mechanics of interbody spinal fusion. Analysis of critical bone graft area.
pubmed:affiliation
Robert Wood Johnson Medical School, New Brunswick, New Jersey.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't