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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
7
|
| pubmed:dateCreated |
1993-10-7
|
| pubmed:abstractText |
Cytotoxic T lymphocyte (CTL) induction usually follows processing of antigens via endogenous pathways before presentation on the cell surface in association with MHC class I molecules. Soluble antigens do not, in general, induce specific CTL responses. Here, Syamal Raychaudhuri and John Morrow suggest that a novel adjuvant formulation can elicit CTL responses to soluble antigens and discuss the implications for vaccine development.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
0167-5699
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
14
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
344-8
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:8363723-Adjuvants, Immunologic,
pubmed-meshheading:8363723-Animals,
pubmed-meshheading:8363723-Antigens, CD8,
pubmed-meshheading:8363723-Histocompatibility Antigens Class I,
pubmed-meshheading:8363723-Humans,
pubmed-meshheading:8363723-Phagocytes,
pubmed-meshheading:8363723-Proteins,
pubmed-meshheading:8363723-T-Lymphocytes, Cytotoxic
|
| pubmed:year |
1993
|
| pubmed:articleTitle |
Can soluble antigens induce CD8+ cytotoxic T-cell responses? A paradox revisited.
|
| pubmed:affiliation |
IDEC Pharmaceuticals Corporation, La Jolla, CA 92037.
|
| pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, U.S. Gov't, P.H.S.,
Review,
Research Support, Non-U.S. Gov't
|