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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
1993-9-30
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pubmed:abstractText |
Enumeration of malignant cells in Sézary syndrome often relies on the identification of the Sézary cell nucleus. This morphologic method is, however, nonspecific and unreliable in the enumeration of the proportion of malignant lymphocytes in peripheral blood of patients with Sézary syndrome. Malignant lymphocytes of patients with mycosis fungoides and Sézary syndrome are often characterized by multiple chromosome aberrations. Herein, we demonstrate that fluorescent in situ hybridization can visualize and accurately enumerate malignant aneuploid mononuclear cells in a patient with Sézary syndrome.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0003-987X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
129
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1141-5
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pubmed:dateRevised |
2008-3-17
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pubmed:meshHeading |
pubmed-meshheading:8363397-Antigens, CD8,
pubmed-meshheading:8363397-Chromosome Aberrations,
pubmed-meshheading:8363397-Chromosomes, Human, Pair 17,
pubmed-meshheading:8363397-DNA, Neoplasm,
pubmed-meshheading:8363397-Flow Cytometry,
pubmed-meshheading:8363397-Humans,
pubmed-meshheading:8363397-In Situ Hybridization, Fluorescence,
pubmed-meshheading:8363397-Karyotyping,
pubmed-meshheading:8363397-Metaphase,
pubmed-meshheading:8363397-Ploidies,
pubmed-meshheading:8363397-Sezary Syndrome,
pubmed-meshheading:8363397-Skin Neoplasms,
pubmed-meshheading:8363397-T-Lymphocytes,
pubmed-meshheading:8363397-Tumor Cells, Cultured
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pubmed:year |
1993
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pubmed:articleTitle |
Aneuploid malignant T cells from a patient with Sézary syndrome can be visualized by in situ hybridization.
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pubmed:affiliation |
Department of Cytogenetics, Danish Cancer Society.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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