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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1993-9-29
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pubmed:databankReference |
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pubmed:abstractText |
Sequences related to the Staphylococcus aureus accessory gene regulator (agr) were demonstrated in S. lugdunensis by Southern blot analysis of 13 strains and sequencing of the S. lugdunensis agr-like locus (agr-sl). Northern blot analysis of cellular RNA revealed the presence of a transcript having homology with the agr-P3 transcript (RNAIII) for three of the six strains tested. The three strains containing this transcript produce a hemolysin with phenotypic properties similar to that of S. aureus delta-hemolysin. Nevertheless, unlike agr-P3 from S. aureus, agr-sl does not encode any potential peptide homologous to S. aureus delta-hemolysin, suggesting that the hemolytic activity detected in S. lugdunensis is encoded elsewhere and may be controlled by agr-sl.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0378-1097
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
111
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pubmed:geneSymbol |
agr
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
115-22
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:8359673-Amino Acid Sequence,
pubmed-meshheading:8359673-Bacterial Proteins,
pubmed-meshheading:8359673-Base Sequence,
pubmed-meshheading:8359673-Blotting, Southern,
pubmed-meshheading:8359673-Cloning, Molecular,
pubmed-meshheading:8359673-DNA,
pubmed-meshheading:8359673-Genes, Bacterial,
pubmed-meshheading:8359673-Genes, Regulator,
pubmed-meshheading:8359673-Hemolysin Proteins,
pubmed-meshheading:8359673-Humans,
pubmed-meshheading:8359673-Molecular Sequence Data,
pubmed-meshheading:8359673-Restriction Mapping,
pubmed-meshheading:8359673-Sequence Homology, Amino Acid,
pubmed-meshheading:8359673-Sequence Homology, Nucleic Acid,
pubmed-meshheading:8359673-Species Specificity,
pubmed-meshheading:8359673-Staphylococcus,
pubmed-meshheading:8359673-Staphylococcus aureus,
pubmed-meshheading:8359673-Transcription, Genetic
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pubmed:year |
1993
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pubmed:articleTitle |
Agr-related sequences in Staphylococcus lugdunensis.
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pubmed:affiliation |
Département de Recherche en Bactériologie Médicale, Lyon, France.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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