Linked Life Data

8359659

Source:http://linkedlifedata.com/resource/pubmed/id/8359659

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1993-9-30
pubmed:abstractText
The overrepresentation of particular HLA alleles in patients with celiac disease was first noted two decades ago. Several lines of evidence obtained during the last years strongly suggest that a particular HLA-DQ heterodimer, encoded by the DQA1*0501 and DQB1*0201 genes in cis or trans configuration, confers the primary disease susceptibility. This paper reviews the evidence behind this concept and discusses how this particular DQ molecule may be involved in the pathogenesis.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0016-5085
pubmed:author
pubmed:issnType
Print
pubmed:volume
105
pubmed:geneSymbol
HLA-DQ
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
910-22
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
HLA susceptibility genes in celiac disease: genetic mapping and role in pathogenesis.
pubmed:affiliation
Institute of Transplantation Immunology, University of Oslo, National Hospital, Norway.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't