Linked Life Data

8356086

Source:http://linkedlifedata.com/resource/pubmed/id/8356086

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
16
pubmed:dateCreated
1993-9-23
pubmed:abstractText
Reproduction in vertebrates is regulated by the hypothalamic-pituitary-gonadal axis via neural and hormonal feedback. This axis is also subject to exogenous influences, particularly social signals. In the African cichlid fish Haplochromis burtoni, gonadal development in males is socially regulated. A small fraction of the males, which are brightly colored, maintain territories and aggressively dominate inconspicuously colored nonterritorial males. Here we show through manipulation of the social and endocrine environment that changes in social status and gonadal state are accompanied by soma size changes in a population of gonadotropin-releasing hormone-containing neurons in the ventral forebrain. In territorial males, these cells are significantly larger than in nonterritorial males. When an animal switches from being territorial to nonterritorial through a change in social situation, these cells shrink; in animals that change from nonterritorial to territorial status, the cells enlarge. These gonadotropin-releasing hormone-containing cells project to the pituitary and are ultimately responsible for regulating gonadal growth. This mechanism of socially induced cell size change provides the potential for relatively quick adaptive changes in the neuron-endocrine system without nerve cell addition or death. Since the structure of this regulatory axis is conserved among all vertebrates, other species with socially modulated reproductive physiology may exhibit a similar form of physiological regulation.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/8356086-1460466, http://linkedlifedata.com/resource/pubmed/commentcorrection/8356086-17830959, http://linkedlifedata.com/resource/pubmed/commentcorrection/8356086-198666, http://linkedlifedata.com/resource/pubmed/commentcorrection/8356086-2273091, http://linkedlifedata.com/resource/pubmed/commentcorrection/8356086-2273399, http://linkedlifedata.com/resource/pubmed/commentcorrection/8356086-2689777, http://linkedlifedata.com/resource/pubmed/commentcorrection/8356086-3024317, http://linkedlifedata.com/resource/pubmed/commentcorrection/8356086-395270, http://linkedlifedata.com/resource/pubmed/commentcorrection/8356086-4522389, http://linkedlifedata.com/resource/pubmed/commentcorrection/8356086-7023610, http://linkedlifedata.com/resource/pubmed/commentcorrection/8356086-831271, http://linkedlifedata.com/resource/pubmed/commentcorrection/8356086-865603
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0027-8424
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
90
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
7794-8
pubmed:dateRevised
2010-9-13
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Social regulation of the brain-pituitary-gonadal axis.
pubmed:affiliation
Department of Psychology, Stanford University, CA 94305-2130.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't