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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1993-9-21
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pubmed:abstractText |
Cholelithiasis is extremely unusual in infants and children. Recently, some cases of cholelithiasis associated with total parenteral nutrition (TPN) have been reported. A group of 400 children receiving TPN were evaluated prospectively for the presence of gallstones and sludge in this report. Eight children (2%) were determined by ultrasonography to have developed cholelithiasis. All of these patients had received large amounts of amino acids (> or = 1.8g/kg/day) and relatively low amounts of fat (< or = 1.7g/kg/day) with a high ratio of non-protein: kcal/ml (> 0.8). It was concluded that the administration of large amounts of amino acids and a high ratio of non-protein: kcal/ml enhanced the risk for formation of gallstones and sludge. Conversely, these are prevented by the administration of appropriate amounts of fat.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0023-5679
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
7-11
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:8355476-Adolescent,
pubmed-meshheading:8355476-Amino Acids,
pubmed-meshheading:8355476-Child,
pubmed-meshheading:8355476-Child, Preschool,
pubmed-meshheading:8355476-Cholestasis,
pubmed-meshheading:8355476-Female,
pubmed-meshheading:8355476-Humans,
pubmed-meshheading:8355476-Incidence,
pubmed-meshheading:8355476-Infant,
pubmed-meshheading:8355476-Infant, Newborn,
pubmed-meshheading:8355476-Lipids,
pubmed-meshheading:8355476-Male,
pubmed-meshheading:8355476-Parenteral Nutrition, Total,
pubmed-meshheading:8355476-Prospective Studies
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pubmed:year |
1993
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pubmed:articleTitle |
Increased incidence of cholestasis during total parenteral nutrition in children--factors affecting stone formation.
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pubmed:affiliation |
Department of Pediatric Surgery, Kurume University School of Medicine, Japan.
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pubmed:publicationType |
Journal Article
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